Open Access
Nanocarriers as an emerging platform for cancer therapy
S. Wise
- 01 Jan 2007
1.2K
About: The article was published on 01 Jan 2007. and is currently open access. The article focuses on the topics: Nanocarriers.
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Citations
Antiangiogenic therapy using nanotechnological-based delivery system.
TL;DR: As the authors review here, such exploitation can be achieved by using nanotechnology and RNA-carrying cationic cell-penetrating peptides, for better protection from the enzymatic digestion and enhanced cellular internalization of these biomolecules.
42
Nanodiamonds as Platforms for Biology and Medicine
Han B. Man,Dean Ho +1 more
TL;DR: This review highlights the progress made toward bringing nanodiamonds from the bench to the bedside and demonstrates the ability for NDs to effectively treat chemoresistant tumors in vivo.
42
Nullifying tumor efflux by prolonged endolysosome vesicles: development of low dose anticancer-carbon nanotube drug.
Yeon Kyung Lee,Jungil Choi,Wenping Wang,Soyoung Lee,Tae-Hyun Nam,Wan Sung Choi,Chang-Joon Kim,Jong Kwon Lee,Sang-Hyun Kim,Sang Soo Kang,Dongwoo Khang +10 more
TL;DR: It is demonstrated that the intracellular delivery of amide linked doxorubicin on carbon nanotube can nullify the efflux of cancer cells by achieving prolonged endolysosome delivery and can induce burst release of doxorbicin in an acidic hydrolase environment and, ultimately, can reduce the amount of anticancer drug by 10-fold compared to conventional effective drug dose.
42
Composite Sensor Particles for Tuned SERS Sensing: Microfluidic Synthesis, Properties and Applications.
TL;DR: The platform for size-tuned droplets generation, synthesis of composite microparticles, mechanism for synchronized photopolymerization-photoreduction, tuned silver enforcement, and the impacts of different analytes on differently composed microp articles are systematically investigated in this paper.
41
Magnetic nanoparticle-promoted droplet vaporization for in vivo stimuli-responsive cancer theranostics
Yang Zhou,Ronghui Wang,Zhaogang Teng,Zhigang Wang,Bing Hu,Michael C. Kolios,Hangrong Chen,Nan Zhang,Yanjie Wang,Pan Li,Xing Wu,Guangming Lu,Yu Chen,Yuanyi Zheng,Yuanyi Zheng +14 more
TL;DR: In this article, a magnetic droplet vaporization (MDV) based on nanobiotechnology was developed for efficient magnetic field-responsive cancer theranostics, which can enhance the performance of ultrasound imaging of tumors.
References
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A New Concept for Macromolecular Therapeutics in Cancer Chemotherapy: Mechanism of Tumoritropic Accumulation of Proteins and the Antitumor Agent Smancs
Yasuhiro Matsumura,Hiroshi Maeda +1 more
TL;DR: It is speculated that the tumoritropic accumulation of smancs and other proteins resulted because of the hypervasculature, an enhanced permeability to even macromolecules, and little recovery through either blood vessels or lymphatic vessels in tumors of tumor-bearing mice.
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Multidrug resistance in cancer: role of ATP–dependent transporters
TL;DR: The ability to predict and circumvent drug resistance is likely to improve chemotherapy, and it has become apparent that resistance exists against every effective drug, even the authors' newest agents.
Recent advances with liposomes as pharmaceutical carriers.
TL;DR: For further successful development of this field, promising trends must be identified and exploited, albeit with a clear understanding of the limitations of these approaches.
5.1K
Cancer nanotechnology: opportunities and challenges.
TL;DR: Nanotechnology is a multidisciplinary field, which covers a vast and diverse array of devices derived from engineering, biology, physics and chemistry that can provide essential breakthroughs in the fight against cancer.
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Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance
Leon R. Hirsch,R.J. Stafford,James A. Bankson,S.R. Sershen,Belinda Rivera,Roger E. Price,John D. Hazle,Nancy J. Halas,Jennifer L. West +8 more
TL;DR: In vivo studies under magnetic resonance guidance revealed that exposure to low doses of NIR light in solid tumors treated with metal nanoshells reached average maximum temperatures capable of inducing irreversible tissue damage, and found good correlation with histological findings.
4.1K