Mucins, Mucus, and Goblet Cells

Abstract: Additional file 2. The uncropped image details of the location of SNV rs11960.

TL;DR: Schisandrin A, an active lignan derived from the Schisandra fruit, exhibits anti-inflammatory characteristics as discussed by the authors , which can effectively lower the expression of COX-2 and inducible nitric oxide synthase (iNOS) in 16 HBE cells.

Abstract: Additional file 4. The uncropped image details of the location of SNV rs1800517.

TL;DR: The mucolytic enzyme (i.e. bromelain)-encapsulated co-delivery system was found to enhance mucopenetration of the encapsulated drug from histological analysis using ex vivo porcine intestine tissue and provides a promising solution to the major issues hampering the wide-spread application of MPs in the development of oral drug formulations for biopharmaceuticals and vaccines.

TL;DR: Pulmonary defense against environmental injury depends on airway mucus, which traps inhaled toxins that are then cleared from the lungs by ciliary beating and cough.

TL;DR: The colon mucus is organized in two layers: an inner, stratified mucus layer that is firmly adherent to the epithelial cells and approximately 50 μm thick; and an outer, nonattached layer, usually approximately 100 μm thickness as measured in mouse.

TL;DR: Among selected subjects with COPD, azithromycin taken daily for 1 year, when added to usual treatment, decreased the frequency of exacerbations and improved quality of life but caused hearing decrements in a small percentage of subjects.

TL;DR: The findings suggest that dysregulated MUC5B expression in the lung may be involved in the pathogenesis of pulmonary fibrosis, and a common polymorphism in the promoter of M UC5B is associated with familial interstitial pneumonia and idiopathic pulmonary fibrot.