Molecular characterization of ICEVchVie0 and its disappearance in Vibrio cholerae O1 strains isolated in 2003 in Vietnam
Stefania Bani,Patrizia Nina Mastromarino,Daniela Ceccarelli,An Le Van,Anna Maria Salvia,Quynh Tram Ngo Viet,Duong Huynh Hai,Donatella Bacciu,Piero Cappuccinelli,Mauro M. Colombo +9 more
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TL;DR: Vibrio cholerae O1 strains isolated in the region of Thua Thien Hue (Vietnam) in 2003 showed the same BglI ribotype, irrespective of their site of isolation and resistance pattern, and this finding reinforces the idea that the SXT/R391 family of genetic elements is wide and composite.
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Abstract: We analyzed 28 epidemic Vibrio cholerae O1 strains isolated in the region of Thua Thien Hue (Vietnam) in 2003. Ubiquitous amoxicillin, prevalent aminoglycosides and sporadic erythromycin resistances were observed. All were devoid of plasmids, class 1 integrons and ICEs and showed the same BglI ribotype, irrespective of their site of isolation and resistance pattern. A strain isolated in 1990 in the same area was resistant to amoxicillin and aminoglycosides but characterized by a different ribotype. This strain contained ICEVchVie0, belonging to the SXT/R391 ICE family, devoid of any resistance cluster. The molecular analysis of three conserved and six variable regions outlined an original genetic profile. ICEs not coding for resistance to drugs seem to be more frequent than supposed, and this finding reinforces the idea that the SXT/R391 family of genetic elements is wide and composite. The clearance of ICEVchVie0 in the 2003 epidemic may be explained by the lack of any resistance determinant as a favorable selective marker.
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Evidence for several waves of global transmission in the seventh cholera pandemic
Ankur Mutreja,Dong Wook Kim,Dong Wook Kim,Nicholas R. Thomson,Thomas R. Connor,Jehee Lee,Jehee Lee,Samuel Kariuki,Nicholas J. Croucher,Seon Young Choi,Seon Young Choi,Simon R. Harris,Michael Lebens,Swapan Kumar Niyogi,Eun Jin Kim,Thandavarayan Ramamurthy,Jongsik Chun,James L. N. Wood,John D. Clemens,Cecil Czerkinsky,G. Balakrish Nair,Jan Holmgren,Julian Parkhill,Gordon Dougan +23 more
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Antibiotic resistance mechanisms of Vibrio cholerae.
TL;DR: In this article, the initial identification and subsequent evolution of antibiotic-resistant strains of Vibrio cholerae are discussed. But, the authors do not discuss the evolution of these strains.
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Integrating Conjugative Elements as Vectors of Antibiotic, Mercury, and Quaternary Ammonium Compound Resistance in Marine Aquaculture Environments
TL;DR: These results show the first evidence of ICEs providing rifampin and QAC resistances, suggesting that these mobile genetic elements contribute to the dissemination of antimicrobial, heavy metal, andQAC resistance determinants in aquaculture environments.
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Vibrio cholerae O139 Multiple-Drug Resistance Mediated by Yersinia pestis pIP1202-Like Conjugative Plasmids
Jingcao Pan,Rong Ye,Haoqiu Wang,Hai-Qing Xiang,Wei Zhang,Xinfen Yu,Dong-Mei Meng,Zhe-Sheng He +7 more
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