Mitochondrial creatine kinase activity prevents reactive oxygen species generation: antioxidant role of mitochondrial kinase-dependent ADP re-cycling activity.
Laudiene Evangelista Meyer,Lilia Bender Machado,Ana Paula S. A. Santiago,Wagner Seixas da-Silva,Fernanda G. De Felice,Oliver Holub,Marcus F. Oliveira,Antonio Galina +7 more
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TL;DR: The results presented here indicate that mitochondrial kinase activity performed a key role as a preventive antioxidant against oxidative stress, reducing mitochondrial ROS generation through an ADP-recycling mechanism.
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About: This article is published in Journal of Biological Chemistry. The article was published on 08 Dec 2006. and is currently open access. The article focuses on the topics: Mitochondrial ROS & Kinase activity.
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Citations
Proteomic analysis of hippocampal proteins in acrylamide-exposed Wistar rats.
Daichi Nagashima,Daichi Nagashima,Lingyi Zhang,Yuki Kitamura,Yuki Kitamura,Sahoko Ichihara,Eri Watanabe,Cai Zong,Yuko Yamano,Toshihiro Sakurai,Shinji Oikawa,Gaku Ichihara +11 more
TL;DR: Comparison with a previous proteomic study on hippocampal proteins in rats exposed to 1-bromopropane identified triosephosphate isomerase, mitochondrial creatinine kinase U-type, creatine kinase β-type and proteasome subunit α type-1 as proteins affected by exposure to acrylamide and 1- bromoproane, suggesting a common mechanism of neurotoxicity for soft electrophiles.
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Effects of Ultramarathon Running on Mitochondrial Function of Platelets and Oxidative Stress Parameters: A Pilot Study.
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TL;DR: In this article, the authors evaluated changes in mitochondrial function and oxidative stress associated with ultramarathon running and its association with individual race performance and markers of oxidative stress, muscle damage and renal dysfunction.
Hearts of some Antarctic fishes lack mitochondrial creatine kinase.
TL;DR: Overall, CK activity is similar between hearts of red- and white-blooded notothenioids but hearts of icefishes lack MtCK and have higher activities of M-CK in the cytosol compared to red-blooded fishes, which may compromise cardiac function under stressful conditions when ATP supply becomes limiting.
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Creatine Supplementation to Improve Sarcopenia in Chronic Liver Disease: Facts and Perspectives
Riccardo Casciola,L. Leoni,Biagio Cuffari,M. Pecchini,R Menozzi,Antonio Colecchia,Federico Ravaioli +6 more
TL;DR: In this paper , the authors summarise the current evidence for creatine supplementation in advanced chronic liver disease and its complications, primarily in sarcopenic cirrhotic patients, because this condition is known to be associated with poor prognosis and outcomes.
Effects of dietary guanidinoacetic acid on growth performance, guanidinoacetic acid absorption and creatine metabolism of lambs
TL;DR: In this paper , the effects of dietary different levels of GAA on growth performance, GAA absorption and creatine metabolism of lambs were evaluated, and the results showed that, as the GAA content of the diet increased, there was a quadratic change in DMI, with the lowest in the 500 mg/kg group and the highest in the 0 mg/ kg group.
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