MINT, the molecular interaction database: 2012 update
Luana Licata,Leonardo Briganti,Daniele Peluso,Livia Perfetto,Marta Iannuccelli,Eugenia Galeota,Francesca Sacco,A. Palma,Aurelio Pio Nardozza,Elena Santonico,Luisa Castagnoli,Gianni Cesareni +11 more
TL;DR: The growth of the database, the major changes in curation policy and a new algorithm to assign a confidence to each interaction are reported here.
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Abstract: The Molecular INTeraction Database (MINT, http://mint.bio.uniroma2.it/mint/) is a public repository for protein-protein interactions (PPI) reported in peer-reviewed journals. The database grows steadily over the years and at September 2011 contains approximately 235,000 binary interactions captured from over 4750 publications. The web interface allows the users to search, visualize and download interactions data. MINT is one of the members of the International Molecular Exchange consortium (IMEx) and adopts the Molecular Interaction Ontology of the Proteomics Standard Initiative (PSI-MI) standards for curation and data exchange. MINT data are freely accessible and downloadable at http://mint.bio.uniroma2.it/mint/download.do. We report here the growth of the database, the major changes in curation policy and a new algorithm to assign a confidence to each interaction.
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Citations
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Andreas Zanzoni,Luisa Montecchi-Palazzi,Michele Quondam,Gabriele Ausiello,Manuela Helmer-Citterich,Gianni Cesareni +5 more
TL;DR: MINT, a database designed to store data on functional interactions between proteins, consists of entries extracted from the scientific literature by expert curators assisted by ‘MINT Assistant’, a software that targets abstracts containing interaction information and presents them to the curator in a user‐friendly format.
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The EMBL Nucleotide Sequence Database
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