Journal Article10.1016/J.BPG.2006.03.007
Microlithiasis and sludge
86
TL;DR: 'Sludge' is the solid material which results from the slow settling of particles dispersed in a liquid medium, and microlithiasis and sludge in bile may cause colicky pain, cholecystitis, cholangitis, and acute pancreatitis and are thus of clinical relevance.
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Abstract: 'Sludge' is the solid material which results from the slow settling of particles dispersed in a liquid medium. Biliary sludge in the gallbladder can be detected by transabdominal ultrasonography, and the typical echoes derive mainly from pigment precipitates mixed with cholesterol crystals. A portion of biliary sludge contains comparatively large particles (1-3 mm) called microliths, the formation of which is an obligatory intermediate step in the development of all types of gallstone. Microlithiasis and sludge in bile may cause colicky pain, cholecystitis, cholangitis, and acute pancreatitis, and are thus of clinical relevance. In these patients treatment follows the guidelines of symptomatic gallstone disease, and strategies include long-term application of ursodeoxycholic acid, endoscopic papillotomy, or preferably laparoscopic cholecystectomy.
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Citations
EASL Clinical Practice Guidelines on the prevention, diagnosis and treatment of gallstones
Frank Lammert,M. Acalovschi,Giorgio Ercolani,K.J. van Erpecum,Kurinchi Selvan Gurusamy,C.J.H.M. van Laarhoven,Piero Portincasa +6 more
TL;DR: The EASL Clinical Practice Guidelines (CPG) on the prevention, diagnosis and therapy of gallstones aim to provide current recommendations on the following issues.
535
Acute Pancreatitis: Etiology, Clinical Presentation, Diagnosis, and Therapy
TL;DR: The causes, diagnosis, imaging findings, therapy, and complications of acute pancreatitis are discussed.
207
Gallstone disease in children
Jan Svensson,Erica Makin +1 more
TL;DR: The pathophysiology, genetics, and predisposing factors for developing gallstones are outlined and a review of the literature on the current and more novel medical and surgical techniques to treat this interesting disease is included.
81
Gallstone Disease in Children
Matthew J. Giefer,Richard A. Kozarek +1 more
- 01 Jan 2014
TL;DR: This chapter discusses the diagnosis and medical management of gallstone-related issues including cholecystitis, choledocholithiasis, gallstone pancreatitis, biliary pain, cholangitis, Mirizzi’s syndrome, and sphincter of Oddi dysfunction.
72
Frequency and prognosis of acute pancreatitis associated with fulminant or non-fulminant acute hepatitis A: A systematic review.
Samir Haffar,Fateh Bazerbachi,Larry J. Prokop,Kymberly D. Watt,M. Hassan Murad,Suresh T. Chari +5 more
TL;DR: A systematic review of the frequency and prognosis of AP associated with fulminant or non-fulminant acute hepatitis A and developed a tool for risk of bias assessment of case reports and case-series and applied to the included studies.
64
References
Biliary sludge as a cause of acute pancreatitis.
TL;DR: The presence of biliary sludge appeared to increase the likelihood of recurrent attacks of pancreatitis and is an underestimated cause of acute idiopathic pancreatitis.
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•Journal Article
Gallstone formation after rapid weight loss: a prospective study in patients undergoing gastric bypass surgery for treatment of morbid obesity.
TL;DR: The present study evaluated the incidence of gallstone formation in 105 morbidly obese patients undergoing rapid weight loss after proximal gastric bypass surgery, finding no significant differences between patients who developed gallstones or sludge and those who did not.
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Incidence, natural history, and risk factors for biliary sludge and stones during pregnancy
TL;DR: Investigation of the incidence, natural history, and risk factors for biliary sludge and stones during pregnancy and the postpartum in 3,254 women at an army medical center concluded that Prepregnancy obesity and serum leptin are strong risk Factors for pregnancy‐associated gallbladder disease.
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Reversible ceftriaxone-associated biliary pseudolithiasis in children
TL;DR: Serial abdominal ultrasonography was performed in 37 children being treated with ceftriaxone for serious infections, finding biliary concrements developed in 16 patients, causing symptoms in 3, one of whom also had urolithiasis with renal colic and obstructive ureteropyelectasia.
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Origin and fate of biliary sludge.
TL;DR: The origin of biliary sludge ultrasonic echoes was studied, using an ex vivo liver-gallbladder preparation, and the outcome of a group of patients identified to have gallbladder sludge by ultrasonography was determined.
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