Journal Article10.1002/1521-4095(200007)12:14<1067::AID-ADMA1067>3.0.CO;2-M
Microcontact Printing of Proteins
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TL;DR: Surface-bound mole-cules find application in biosensors, chromatography, diagnos-tic immunoassays, cell culturing, DNA microarrays, and otheranalytical procedures and are driving efforts to minia-turize biological assays and to conduct many assays in paral-lel.
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Abstract: Surface-bound mole-cules find application in biosensors, chromatography, diagnos-tic immunoassays, cell culturing, DNA microarrays, and otheranalytical procedures. Among these applications, diagnosticimmunoassays and DNA sensing are driving efforts to minia-turize biological assays and to conduct many assays in paral-lel. This trend offers several advantages. In small volumes,biochemical reactions may not be diffusion-limited and maythus be more efficient; less reagent and sample solution areused, lowering costs per test.
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References
Adsorption of proteins onto surfaces containing end-attached oligo(ethylene oxide): a model system using self-assembled monolayers
TL;DR: In this paper, the adsorption of four proteins-fibrinogen, lysozyme, pyruvate kinase, and RNAse A-to self-assembled monolayers (SAMs) on gold was studied.
1.7K
Patterning proteins and cells using soft lithography
TL;DR: This review describes the pattering of proteins and cells using a non-photolithographic microfabrication technology, which consists of a set of related techniques, each of which uses stamps or channels fabricated in an elastomeric ('soft') material for pattern transfer.
1.6K
Molecular Conformation in Oligo(ethylene glycol)-Terminated Self-Assembled Monolayers on Gold and Silver Surfaces Determines Their Ability To Resist Protein Adsorption
TL;DR: In this paper, the authors reported data from infrared absorption (FTIR) and X-ray photoelectron spectroscopies that correlate the molecular conformation of oligo(ethylene glycol) (OEG)-terminated self-assembled alkanethiolate monolayers (SAMs) with the ability of these films to resist protein adsorption.
1.3K
Protein adsorption and materials biocompatibility: A tutorial review and suggested hypotheses
Joseph D. Andrade,Vladimir Hlady +1 more
- 01 Jan 1986
TL;DR: A comprehensive review of protein adsorption at solid-liquid interfaces is presented in this article, including a brief overview of protein structure and the principles of protein adaption. Qualitative “rules of thumb” of protein Adaption are also presented.
873
Constraints on Microcontact Printing Imposed by Stamp Deformation
TL;DR: In this paper, the impact of stamp deformation on the dimensional stability of the microcontact printing process is investigated. But the authors consider limitations imposed due to reversible deformation of a single stamp.
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