Methods for rapid forensic analysis of mitochondrial dna

TL;DR: In this paper, the authors present methods for rapid forensic investigations by identification of bioagents associated with biowarfare and acts of terrorism or crime, which are also useful for epidemiological investigations by genotyping bioagents.

TL;DR: In this paper, a system and method for automated processing of nucleic acids and other samples includes a disposable container comprising a tray and a flexible barrier, which is configured to seal with a top edge of the tray, providing a closed, aseptic work area within the sealed tray.

TL;DR: In this article, a secondary structure defining databases (SDSDB) is used to determine the identity of a selected bioagent, and/or the origin of the chosen bioagent.

TL;DR: In this paper, the authors present compositions, kits and methods for rapid identification and quantification of bacteria by molecular mass and base composition analysis, which can be used to identify and quantify bacteria.

TL;DR: In this article, a method and an apparatus for sequentially degrading at least a portion of a polymer of backbone repeating units, the polymer having a terminal repeating unit comprised of a nucleophile and a backbone carbonyl carbon distant from the nucleophile, comprising the steps of first initiating attack of said nucleophile upon said backbone carbon by raising the energy level to activate said nucleophase for said attack, and, lastly maintaining the reaction conditions necessary for repeating steps a and b until the portion of the desired is degraded.

TL;DR: In this paper, the use of mass spectrometry to detect length variation in DNA nucleotide sequence repeats (including variants of common alleles), such as microsatellites and short tandem repeats, and to DNA sequences provided as primers for the analysis of DNA tandem nucleotide repeat polymorphisms at specific loci on specific chromosomes.

TL;DR: PCRNAs for sa442 and mecA genes were 100% sensitive and specific for detecting Staphylococcus aureus and methicillin resistance in S. aUREus but was less accurate for methichill resistance in coagulase-negative staphylitisci.

TL;DR: This constitutes the first report demonstrating the ionization and detection of PCR products by mass spectrometry with mass precision and accuracy for assignment of such modifications or substitutions.