Patent
Method for simultaneously measuring T2* and diffusion with magnetic resonance imaging
Sean B. Fain,Walter F. Block,James H. Holmes,Rafael O'Halloran +3 more
- 22 Apr 2009
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TL;DR: In this paper, a method for measuring the apparent transverse relaxation time (T* 2 ) and apparent diffusion coefficient (ADC) of a hyperpolarized gas in a single breath-hold and with a single dose of the hypoxia contrast agent, is provided.
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Abstract: A method for measuring the apparent transverse relaxation time (“T* 2 ”) and apparent diffusion coefficient (“ADC”) of a hyperpolarized gas in a single breath-hold and consequently, with a single dose of the hyperpolarized gas contrast agent, is provided. The method employs a multiple-echo projection acquisition based pulse sequence. Individual images are reconstructed from data acquired during each of the individual echo times. Subsequently, T* 2 and ADC are calculated using these reconstructed images. Furthermore, the method produces images indicative of ADC that have isotropic resolution, allowing for more reliable image registration. The inter-echo spacing and diffusion weighting b-value are varied during the pulse sequence employed when practicing the present invention; thus, a significant separation between the effects of diffusion and T* 2 decay on the detected MR signals is possible. This separation allows for reliable measurements of these two parameters from a single echo-train.
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Citations
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Reed F. Busse,James H. Holmes,Philip James Beatty,Kang Wang,Frank R. Korosec +4 more
- 18 Mar 2011
TL;DR: In this paper, the authors describe a method for improving image data acquisition and processing in accelerated dynamic magnetic resonance imaging sequences, where a method includes an acquisition sequence configured to acquire an undersampled set of magnetic resonance data.
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Hua Guo,Feng Huang,Ma Xiaodong,Wenchuan Wu,Chun Yuan +4 more
- 14 Nov 2012
TL;DR: In this article, a method for diffusion magnetic resonance imaging is proposed, which consists of performing sampling on an object at N diffusion weighted directions to acquire undersampled but complementary k-space data, combining the complementary data from different directions to obtain a full sampled kspace data.
9
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James H. Holmes,Philip James Beatty +1 more
- 14 Sep 2012
TL;DR: In this article, a method for processing magnetic resonance (MR) data according to a process including applying a density filter to blades of k-space data rotated about a section of K-space.
5
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Systems and methods for joint reconstruction of quantitative t2 and adc maps
Daniel B. Ennis,Eric Aliotta +1 more
- 25 Jan 2017
TL;DR: In this paper, a method for generating apparent diffusion coefficient maps and T2 maps of an object is presented. But the method requires a large number of motion encoding gradients to acquire diffusion weighted imaging (DWI) data at a given echo time (TE).
1
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