Patent
Method for classifying tumour cells
Jun Hou,Joan Geertrudis Jacobus Victor Aerts,Franklin Gerardus Grosveld +2 more
- 30 Nov 2012
3
TL;DR: In this paper, a method for preparing an optimised gene signature for assigning a NSCLC sample to one or more classes, comprising subjecting a gene signature set forth in Table 12 herein to nearest shrunken centroid analysis, was presented.
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Abstract: The invention relates to a method for preparing an optimised gene signature for assigning a NSCLC sample to one or more NSCLC classes, comprising subjecting a gene signature set forth in Table 12 herein to nearest shrunken centroid analysis to identify one or more subgroups of gene classifiers corresponding to one or more of classes 1 to 6 identified in Table 12, and validating the performance of the selected classifiers by K-fold or leave-one-out cross-validation.
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Patent
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Nora Berois,Diego Touya,Mario Varangot,Eduardo Osinaga +3 more
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TL;DR: In this article, the authors present a process, assays and methods for determining the likelihood of chemotherapy resistance and predicting response to chemotherapy in a subject with cancer, in an embodiment of the subject has lung cancer.
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TL;DR: In this paper, the authors showed that cellular cannibal cells can undergo senescence after entosis in vivo and that the tumor suppressive protein p53 act as a repressor of this phenomenon.
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Biomarkers for diagnosis of lung cancer
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- 07 Jan 2020
TL;DR: In this article, the authors proposed a means and methods for diagnosing, assessing the level of severity and selecting methods of treating non-small cell lung cancer (NSCLC).
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Rafael A. Irizarry,Bridget G. Hobbs,Francois Collin,Yasmin Beazer-Barclay,Kristen J. Antonellis,Uwe Scherf,Terence P. Speed +6 more
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