Journal Article10.1021/ACS.ORGLETT.5B01698
Metal-Free Reduction of Aromatic and Aliphatic Nitro Compounds to Amines: A HSiCl3-Mediated Reaction of Wide General Applicability.
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TL;DR: A new, mild, metal-free, HSiCl3-mediated reduction of both aromatic and aliphatic nitro groups to amines that is of wide general applicability, tolerant of many functional groups, and respectful of the stereochemical integrity of stereocenters is reported.
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About: This article is published in Organic Letters. The article was published on 11 Aug 2015. The article focuses on the topics: Nitro.
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Citations
Recent Developments in the Reduction of Aromatic and Aliphatic Nitro Compounds to Amines
TL;DR: The review will offer an overview of the different possible methodologies available for the nitro group reduction, with special attention on the most efficient and selective nitro reduction methods for chiral amino groups.
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Metal-Free Reduction of Aromatic Nitro Compounds to Aromatic Amines with B2pin2 in Isopropanol
TL;DR: A metal-free reduction of aromatic nitro compounds to the corresponding amines has been achieved by a combination of B2pin2 and KOtBu in isopropanol.
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Whole Cells as Biocatalysts in Organic Transformations
TL;DR: This review surveys the most recent developments in the enantioselective reduction of carbon-carbon double bonds and prochiral ketones and the oxidation of pro chiral sulfides using whole cells as biocatalytic systems.
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A new magnetically recyclable heterogeneous palladium(II) as a green catalyst for Suzuki-Miyaura cross-coupling and reduction of nitroarenes in aqueous medium at room temperature
Vishal Kandathil,Tuhin S. Koley,K. Manjunatha,Ramesh B. Dateer,Rangappa S. Keri,B. S. Sasidhar,Shivaputra A. Patil,Siddappa A. Patil +7 more
TL;DR: In this paper, a new stable and powerful magnetic nanoparticle supported Schiff base-palladium(II) (MNPs@SB-Pd) nanomagnetic catalyst was synthesized.
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References
Selective Catalytic Hydrogenation of Functionalized Nitroarenes: An Update
TL;DR: In this paper, the main focus is on catalytic systems capable of reducing nitro groups with very high chemoselectivity in substrates containing carbon-carbon or carbon-nitrogen double or triple bonds, carbonyl or benzyl groups, and multiple Cl, Br or I substituents.
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Catalytic syntheses of aromatic amines
TL;DR: The most important manufacturing processes for aniline and other bulk arylamines are based on the continuous catalytic hydrogenation of nitro compounds, employing heterogeneous copper, nickel or platinum-group metals as discussed by the authors.
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General and Selective Iron-Catalyzed Transfer Hydrogenation of Nitroarenes without Base
Gerrit Wienhöfer,Iván Sorribes,Albert Boddien,Felix A. Westerhaus,Kathrin Junge,Henrik Junge,Rosa Llusar,Matthias Beller +7 more
TL;DR: The first well-defined iron-based catalyst system for the reduction of nitroarenes to anilines has been developed applying formic acid as reducing agent, constituting a rare example of base-free transfer hydrogenations.
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Iron-catalyzed selective reduction of nitroarenes to anilines using organosilanes
TL;DR: The iron-catalyzed reduction of aromatic nitro compounds to the corresponding anilines applying organosilanes is reported, selectively reduced tolerating a wide range of functional groups.
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