Metabolic Resource Allocation in Individual Microbes Determines Ecosystem Interactions and Spatial Dynamics
William R. Harcombe,William J. Riehl,Ilija Dukovski,Brian R. Granger,Alex Betts,Alex H. Lang,Gracia Bonilla,Amrita Kar,Nicholas Leiby,Pankaj Mehta,Christopher J. Marx,Daniel Segrè +11 more
TL;DR: A modeling framework that integrates dynamic flux balance analysis with diffusion on a lattice and applied to engineered communities predicted and experimentally confirmed the species ratio to which a two-species mutualistic consortium converges and the equilibrium composition of a newly engineered three-member community.
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About: This article is published in Cell Reports. The article was published on 22 May 2014. and is currently open access.
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Citations
Metabolite toxicity slows local diversity loss during expansion of a microbial cross-feeding community.
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Functional attractors in microbial community assembly.
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TL;DR: In this article, the reproducibility and variability of microbial community assembly were investigated in replicate glucose-limited habitats and it was shown that the previously observed family-level convergence in these habitats reflects a reproducible metabolic organization.
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A systems-wide understanding of photosynthetic acclimation in algae and higher plants.
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TL;DR: This review aims to provide a retrospective analysis of multidisciplinary photosynthetic acclimation research carried out by members of the Marie Curie Initial Training Project, AccliPhot, placing the results in a wider context.
References
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What is flux balance analysis
TL;DR: This primer covers the theoretical basis of the approach, several practical examples and a software toolbox for performing the calculations.