Melanoma epidemiology and trends.

TL;DR: Melanoma may be preventable by regular sunscreen use in adults, and 10 years after trial cessation, 11 new primary melanomas had been identified in the daily sunscreen group, and 22 in the discretionary group, which represented a reduction of the observed rate.

TL;DR: It is imperative that research efforts achieve better understanding of the risk factors and etiology of disease, with the goal to halt and reverse the progressive trend of rising incidence and mortality from melanoma.

TL;DR: Findings provide support that primary and secondary prevention can halt and reverse the observed increasing burden of melanoma, and indicate that those prevention measures require further endorsement in many countries.

TL;DR: Therapeutic decisions in stage IV patients should be primarily made by an interdisciplinary oncology team ('Tumour Board'), based on systematic literature reviews and experts' experience.

TL;DR: Role of country, inclusion of controls with dermatological diseases and other study features seemed to suggest that "well conducted" studies supported the intermittent sun Exposure hypothesis: a positive association for intermittent sun exposure and an inverse association with a high continuous pattern of sun exposure.

TL;DR: Skin cancers, predominantly basal-cell and squamous-cell carcinomas, have accounted for an estimated 40 percent of all cancers in the United States in recent years, and their frequency has been increasing.

TL;DR: A systematic review using results of all published case‐control studies which have assessed incident melanoma, sun exposure and sunburn shows the specificity of the positive association between melanoma risk and intermittent sun exposure, in contrast to a reduced risk with high levels of occupational exposure.

TL;DR: The estimates show the substantial burden of cancer in European Union populations, but there are also indications of effects of past preventive measures and there is scope for further intervention.