Book Chapter10.1017/9781316492376.014
Medication-Resistant Epilepsy in Adults
Martin Holtkamp,Felix Benninger +1 more
- 31 Aug 2020
- pp 158-170
8
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Citations
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Targeted Treatment of Migrating Partial Seizures of Infancy with Quinidine (I6-2B)
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141
•Journal Article
Progressive Hippocampal And Extrahippocampal Atrophy In Drug Resistant Epilepsy
TL;DR: Experimental data indicate that epileptogenesis in developing brain may not require significant neuronal loss, which is in keeping with clinical observations that progressive cognitive and behavioural impairment may occur in patients with no detectable brain atrophy.
121
•Journal Article
The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling
Peggy P. Hsu,Seong A. Kang,Jonathan Rameseder,Yi Zhang,Kathleen Ottina,Daniel Lim,Timothy R. Peterson,Yongmun Choi,Nathanael S. Gray,Michael B. Yaffe,Jarrod A. Marto,David M. Sabatini +11 more
TL;DR: In this paper, the mTOR-regulated phosphoproteome was defined by quantitative mass spectrometry and characterized the primary sequence motif specificity of mTOR using positional scanning peptide libraries.
47
Clinical and video-polygraphic features of epileptic spasms in adults with corticl migration disorders
TL;DR: Ictal polygraphic studies showed a positive, diffuse, high amplitude slow wave activity during spasms, with superimposed fast activity, followed by a diffuse flattening in all cases with a typical muscle pattern.
38
References
In-session seizures during low-frequency repetitive transcranial magnetic stimulation in patients with epilepsy
Alexander Rotenberg,Alexander Rotenberg,Erica Hyunji Bae,Paul A. Muller,James J. Riviello,Blaise F. D. Bourgeois,Andrew S. Blum,Alvaro Pascual-Leone +7 more
TL;DR: It is noteworthy from the perspective of safety and tolerability that seizures during rTMS in this series were similar to the patients' habitual seizures, occurred in patients with epilepsy with baseline seizure frequency exceeding one per day, and did not correlate with a poor neurological outcome or with absence of clinical response to rT MS.
52
Effect of dosage failed of first antiepileptic drug on subsequent outcome.
TL;DR: The effect of the doses at which the first and second AED regimens failed on subsequent outcomes in a population of adults with newly diagnosed epilepsy followed for up to 20 years is explored.
51
Interrater reliability of the international consensus definition of drug-resistant epilepsy: A pilot study
TL;DR: The definition appeared to have a high degree of interrater reliability in this setting, and there was absolute agreement between the raters in 141 patients in the level 2 classification of drug-resistant or drug-responsive epilepsy.
51
Estimating the cost of epilepsy.
TL;DR: The variety of approaches, techniques, and data sources used in cost-of-illness (COI) research are described and guidance is given to researchers and other professionals in the epilepsy field who are interested in conducting and/or critically evaluating re- search on the cost of epilepsy.
51
Laser Ablation in Pediatric Epilepsy
TL;DR: Laser ablation is an emerging, minimally invasive treatment for selected children with intractable focal epilepsy with improved procedural morbidity and improved neuropsychological outcome when compared with standard open surgical resection.
51
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