Mechanisms That Regulate the Function of the Selectins and Their Ligands

TL;DR: The developmentally regulated acquisition of E-selectin inducibility during embryogenesis likely involves changes in signal transduction cascades, transcription factors, and/or chromatin accessibility that specify inducible expression within the endothelial lineage and further restrict in Ducibility to particular endothelial subpopulations.

TL;DR: For most, if not all allergens, along with prolonged allergenic contacts, the role of Th2 cells as effector cells gradually increases given reduced longevity of Th1 responses, but distinct effector roles of allergen-specific Tc1 and Tc2 have been postulated.

TL;DR: Using nanofiltration membranes for the recovery of phosphorous with a second type of technology for the Recovery of nitrogen is suggest to be a viable process.

TL;DR: It is reported for the first time that MAdCAM-1 is normally present in human liver and is further induced upon TNFα and methylamine stimulation resulting in the recruitment of mucosal cells to the liver, thus sustaining a destructive inflammatoty influx responsible for the establishment of chronic inflammation.

TL;DR: Rolling of leukocytes on vascular endothelial cells, an early event in inflammation, can be reproduced in vitro on artificial lipid bilayers containing purified CD62, a selectin also named PADGEM and GMP-140 that is inducible on endothelial Cells.

TL;DR: Of considerable interest is the recent discovery that some chemokines function as HIV-suppressive factors by interacting with chemokine receptors which, together with CD4, were recognized as the binding sites for HIV-1.

TL;DR: Endothelial leukocyte adhesion molecule-1 (ELAM-1), a cell surface glycoprotein expressed by cytokine-activated endothelium, mediates the adhesion of blood neutrophils and may be a member of a nascent gene family of cell surface molecules involved in the regulation of inflammatory and immunological events at the interface of vessel wall and blood.