Measuring and using light in the melanopsin age
Robert J. Lucas,Stuart N. Peirson,David M. Berson,Timothy M. Brown,Howard M. Cooper,Charles A. Czeisler,Mariana G. Figueiro,Paul D. Gamlin,Steven W. Lockley,John O’Hagan,Luke L. A. Price,Ignacio Provencio,Debra J. Skene,George C. Brainard +13 more
TL;DR: A new light-measurement strategy taking account of the complex photoreceptive inputs to these non-visual responses is proposed for use by researchers, and simple suggestions for artificial/architectural lighting are provided for regulatory authorities, lighting manufacturers, designers, and engineers.
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About: This article is published in Trends in Neurosciences. The article was published on 01 Jan 2014. and is currently open access. The article focuses on the topics: Melanopsin & Intrinsically photosensitive retinal ganglion cells.
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References
Phototransduction by retinal ganglion cells that set the circadian clock.
TL;DR: It is shown that retinal ganglion cells innervating the SCN are intrinsically photosensitive, and depolarized in response to light even when all synaptic input from rods and cones was blocked.
3.6K
Melanopsin-Containing Retinal Ganglion Cells: Architecture, Projections, and Intrinsic Photosensitivity
TL;DR: It is shown that melanopsin is present in cell bodies, dendrites, and proximal axonal segments of a subset of rat RGCs, most likely the visual pigment of phototransducing R GCs that set the circadian clock and initiate other non–image-forming visual functions.
2.7K
Action Spectrum for Melatonin Regulation in Humans: Evidence for a Novel Circadian Photoreceptor
George C. Brainard,John P. Hanifin,Jeffrey M. Greeson,Brenda Byrne,Gena Glickman,Edward Gerner,Mark D. Rollag +6 more
TL;DR: The results suggest that, in humans, a single photopigment may be primarily responsible for melatonin suppression, and its peak absorbance appears to be distinct from that of rod and cone cellphotopigments for vision.
1.9K
Light Suppresses Melatonin Secretion in Humans
TL;DR: Findings establish that the human response to light is qualitatively similar to that of other mammals.
1.9K
An action spectrum for melatonin suppression: evidence for a novel non‐rod, non‐cone photoreceptor system in humans
TL;DR: The data strongly support a primary role for a novel short‐wavelength photopigment in light‐induced melatonin suppression and provide the first direct evidence of a non‐rod, non‐cone photoreceptive system in humans.
1.4K