Measuring and using light in the melanopsin age
Robert J. Lucas,Stuart N. Peirson,David M. Berson,Timothy M. Brown,Howard M. Cooper,Charles A. Czeisler,Mariana G. Figueiro,Paul D. Gamlin,Steven W. Lockley,John O’Hagan,Luke L. A. Price,Ignacio Provencio,Debra J. Skene,George C. Brainard +13 more
TL;DR: A new light-measurement strategy taking account of the complex photoreceptive inputs to these non-visual responses is proposed for use by researchers, and simple suggestions for artificial/architectural lighting are provided for regulatory authorities, lighting manufacturers, designers, and engineers.
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About: This article is published in Trends in Neurosciences. The article was published on 01 Jan 2014. and is currently open access. The article focuses on the topics: Melanopsin & Intrinsically photosensitive retinal ganglion cells.
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Citations
Loss of Melanopsin-Expressing Retinal Ganglion Cells in Severely Staged Glaucoma Patients.
TL;DR: This is the first report illustrating histologic evidence for reduced mRGC density in the ganglion cell layer of retinas with severely staged glaucoma compared with age-matched controls, and proposes evaluation of mR GCs integrity as a basis for assessing the pathophysiologic disease progression of glAUcoma.
Transient Downregulation of Melanopsin Expression After Retrograde Tracing or Optic Nerve Injury in Adult Rats.
Francisco M. Nadal-Nicolás,Maria H. Madeira,Manuel Salinas-Navarro,Manuel Jiménez-López,Caridad Galindo-Romero,Arturo Ortín-Martínez,Ana Raquel Santiago,Manuel Vidal-Sanz,Marta Agudo-Barriuso +8 more
TL;DR: There is a transient melanopsin downregulation that should be taken into account when assessing m(+)RGC survival following ON injury or retrograde tracing, and this effect was not observed in the sham groups.
Evening home lighting adversely impacts the circadian system and sleep.
Sean W. Cain,Elise M. McGlashan,Parisa Vidafar,Jona Mustafovska,Simon P N Curran,Xirun Wang,Anas Mohamed,Vineetha Kalavally,Andrew J. K. Phillips +8 more
TL;DR: It is found that nearly half of homes had bright enough light to suppress melatonin by 50%, but with a wide range of individual responses (0–87% suppression for the average home), and greater evening light relative to an individual’s average was associated with increased wakefulness after bedtime.
Quality of sleep and anxiety are related to circadian preference in university students.
TL;DR: In this paper, a cross-sectional study with a quantitative approach, in which 103 undergraduate students answered the Morningness-Eveningness Questionnaire (MEQ) the State and Trait Anxiety Inventory (STAI) and the Pittsburgh Sleep Quality Index (PSQI) and investigated their possible relationships.
Circadian metric – Computation of circadian stimulus using illuminance, correlated colour temperature and colour rendering index
TL;DR: A simple circadian stimulus calculation model for white light sources is presented that enables non-visual planning of illumination installations by lighting designers or lighting design tools and allows retrospective analysis of past non- visual research results in scientific studies, where illuminance and correlated colour temperature were provided.
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