MCM7 Gene Expression versus Risk of Malignancy Index (RMI) for Prediction of Ovarian Malignancy
Nashwa ElSaed
- 07 Dec 2017
- Vol. 4, Iss: 3
About: The article was published on 07 Dec 2017. and is currently open access.
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Citations
Chlamydia trachomatis infection in primary fallopian tube and high-grade serous ovarian cancers: a pilot study.
Mohamed Laban,Eman A. Ibrahim,Alaa S. Hassanin,Magda H. A. Nasreldin,Amal Mansour,Waleed M Khalaf,Ahmed Mohamed Bahaa El-Din,Sherif H Hussain,Mohammed S.E. Elsafty,Ahmad S Hasanien +9 more
TL;DR: This is the first report on relation of CT to the tubal serous cancer, so the responsibility of CT tubal infection in the pathogenesis of primary tubal cancer needs to be considered.
References
The origin and pathogenesis of epithelial ovarian cancer: a proposed unifying theory.
Robert J. Kurman,Ie Ming Shih +1 more
TL;DR: It has been proposed that serous tumors arise from the implantation of epithelium (benign or malignant) from the fallopian tube and preliminary data suggest that mucinous and transitional (Brenner) tumors arose from transitional-type epithelial nests at the tubal-mesothelial junction by a process of metaplasia.
Ki67, PCNA, and MCM proteins: Markers of proliferation in the diagnosis of breast cancer
TL;DR: The functions and properties of all three proteins and their use as markers of proliferation in the diagnosis of breast cancer are described and new findings about the role of Ki67 during the mitotic phase of the cell cycle are revealed.
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Therapeutic strategies in epithelial ovarian cancer
TL;DR: The larger expectation for improved prognosis in ovarian carcinoma is related to the use of the new biological agents, and bevacizumab, a monoclonal antibody directed against VEGF is one of the most investigated and promising molecular targeted drugs.
Clinical Use of Cancer Biomarkers in Epithelial Ovarian Cancer: Updated Guidelines From the European Group on Tumor Markers
György Sölétormos,Michael J. Duffy,Suher Othman Abu Hassan,René H.M. Verheijen,Bengt Tholander,Robert C. Bast,Katja N. Gaarenstroom,Catharine M. Sturgeon,Johannes M.G. Bonfrer,Per Hyltoft Petersen,Hugo Troonen,Gian CarloTorre,Jan Kanty Kulpa,Malgorzata K. Tuxen,Raphael Molina +14 more
TL;DR: At present, CA125 remains the most important biomarker for epithelial ovarian cancer, excluding tumors of mucinous origin.