Maternal thyroid hypofunction and pregnancy outcome.

TL;DR: The aim of the current review is to evaluate the current understanding of the role of selenium and iodine in diabetes with a focus on the biochemical interplay between the elements, their possible role as biomarkers, and their chemical speciation.

TL;DR: The results confirm an association between ID and hypothyroxinemia and hypotriiodothyroninemia in the general adult population without changes in TSH and there was no significant heterogeneity of the results between men, pre- menopausal and post-menopausal women.

TL;DR: The findings indicate that the exposure of gestational mice to TCS results in insulin resistance via thyroid hormones reduction, and TCS exposure in Ng-mice did not cause the insulin resistance or affect PPARγ and GLUT4 expression, and Akt phosphorylation.

TL;DR: It is indicated that subclinical hypothyroidism in pregnancy is associated with an increased risk of developing HDP, and this association exists regardless of the gestational period, so routine screening is only recommended for pregnant women with risk factors for hypothyroxine.

TL;DR: Maternal thyroid function during early pregnancy is an important determinant of early fetal brain development because the fetal thyroid is unable to produce any T4 before 12–14 weeks' gestation.

TL;DR: First-trimester combined screening at 11 weeks of gestation is better than secondtrimester quadruple screening but at 13 weeks has results similar to second-tr pregnancy quadruple screened, except for the comparison between serum integrated screening and combined screening.

TL;DR: It is speculated that the previously reported reduction in intelligence quotient of offspring of women with subclinical hypothyroidism may be related to the effects of prematurity.

TL;DR: First-trimester combined screening at 11 weeks of gestation is better than second- Trimester quadruple screening but at 13 weeks has results similar to second- trimester quadruples screening.