Journal Article10.1016/J.NLM.2012.08.004
Maternal deprivation induces deficits in temporal memory and cognitive flexibility and exaggerates synaptic plasticity in the rat medial prefrontal cortex
Aurélie Baudin,Kevin Blot,Kevin Blot,Catherine Verney,Catherine Verney,Lucie Estevez,Lucie Estevez,Julie Santamaria,Julie Santamaria,Pierre Gressens,Pierre Gressens,Bruno Giros,Satoru Otani,Satoru Otani,Valérie Daugé,Valérie Daugé,Laurent Naudon,Laurent Naudon +17 more
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TL;DR: Evidence is provided that maternal deprivation in adults leads in adults to an alteration of the cognitive abilities dependent on the PFC, and to an exaggerated synaptic plasticity in this region, which may contribute to the impairments in the cognitive tasks.
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About: This article is published in Neurobiology of Learning and Memory. The article was published on 01 Oct 2012. The article focuses on the topics: Prefrontal cortex & Hippocampus.
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Early-life stress affects the structural and functional plasticity of the medial prefrontal cortex in adolescent rats.
Agnieszka Chocyk,Bartosz Bobula,Dorota Dudys,Aleksandra Przyborowska,Iwona Majcher-Maślanka,Grzegorz Hess,Krzysztof Wędzony +6 more
TL;DR: The results of this study indicate that ELS has a significant impact on the structural and functional plasticity of the mPFC in adolescents, and ELS‐induced adaptive plasticity may underlie the pathomechanisms of some early‐onset psychopathologies observed in adolescents.
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Aerobic Exercise as a Tool to Improve Hippocampal Plasticity and Function in Humans: Practical Implications for Mental Health Treatment.
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References
Hippocampal neurochemistry is involved in the behavioural effects of neonatal maternal separation and their reversal by post-weaning environmental enrichment: A magnetic resonance study
Jiaojie Hui,Zhijun Zhang,Shan-shan Liu,Guangjun Xi,Xiangrong Zhang,Gao-Jun Teng,Kevin C. Chan,Ed X. Wu,Binbin Nie,Baoci Shan,Lingjiang Li,Gavin P. Reynolds +11 more
TL;DR: Results indicate the involvement of hippocampal neurochemistry in the behavioural changes that result from early stressful life events and their modification by post-weaning EE, and changes in NAA appear to be a sensitive correlate of these behavioural effects.
90
Prenatal cocaine exposure impairs selective attention: Evidence from serial reversal and extradimensional shift tasks
Hugh Garavan,Russell E. Morgan,Charles F. Mactutus,David A. Levitsky,Rosemarie M. Booze,Barbara J. Strupp +5 more
TL;DR: Data provide clear evidence that prenatal cocaine exposure produces long-lasting cognitive dysfunction, but they also underscore the specificity of the impairment.
87
Effect of exercise on learning and memory in a rat model of developmental stress
TL;DR: Examination of the effects of maternal separation and exercise on learning and memory in rats indicates that maternal separation had little effect on the rats whereas exercise enhanced both spatial and recognition memory.
Context-dependent modulation of hippocampal and cortical recruitment during remote spatial memory retrieval.
Joëlle Lopez,Karin Herbeaux,Brigitte Cosquer,Michel Engeln,Christophe Muller,Christine Lazarus,Christian Kelche,Bruno Bontempi,Jean-Christophe Cassel,Anne Pereira de Vasconcelos +9 more
TL;DR: Findings indicate that mPFC and hippocampus recruitment depends on the content and perhaps the strength of the memory and may be influenced by the environmental conditions in which memories are initially formed and subsequently recalled.
80
Neonatal stress alters LTP in freely moving male and female adult rats.
TL;DR: The results of the present study indicate that infant stress alters hippocampal neuroplasticity in such a way that its effect endures into adulthood.
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