Journal Article10.1016/0022-2836(76)90332-6
Mass, length, composition and structure of the filamentous bacterial virus fd.
Steven A. Berkowitz,Loren A. Day +1 more
115
TL;DR: The results provide a basis for the interpretation of X-ray diffraction patterns of oriented fibers oforiented fibers of the virus.
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About: This article is published in Journal of Molecular Biology. The article was published on 15 Apr 1976. The article focuses on the topics: Bacterial virus.
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Citations
Escherichia coli thioredoxin confers processivity on the DNA polymerase activity of the gene 5 protein of bacteriophage T7.
TL;DR: Bacteriophage T7 gene 5 protein has been purified to apparent homogeneity from cells overexpressing its gene several hundred-fold, and DNA synthesis catalyzed by the gene 5protein-thioredoxin complex on a single-stranded DNA template can polymerize thousands of nucleotides without dissociation.
433
Making artificial antibodies: A format for phage display of combinatorial heterodimeric arrays
TL;DR: A phagemid format was developed wherein antibody heavy- and light-chain variable regions were fused to the amino termini of pVII and pIX, respectively, and interacted to form a functional Fv-binding domain on the phage surface.
203
A method for the generation of combinatorial antibody libraries using pIX phage display
TL;DR: The results suggested that the performance of pIX-display libraries can potentially exceed that of the pIII-display format and make it ideally suited for panning a wide variety of target antigens.
198
Basics of Antibody Phage Display Technology
Line Ledsgaard,Mogens Kilstrup,Aneesh Karatt-Vellatt,John McCafferty,Andreas Hougaard Laustsen +4 more
TL;DR: The lifecycle of the M13 phage and the basics of phage display technology are presented together with important factors influencing the success rates ofphage display experiments.
Bacteriophage interactions with mammalian tissue: Therapeutic applications
TL;DR: The direct evidence of the accumulation of bacteriophages in various tissues is discussed, focusing on the unique capability of phages to traverse relatively impermeable barriers in mammals and its relevance to its current applications in therapy.
149
References
Rapid bacteriophage sedimentation in the presence of polyethylene glycol and its application to large-scale virus purification.
TL;DR: Extension of this method to concentration and purification of other viruses and nucleic acids, as well as some preliminary mechanistic studies, are discussed.
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Apparatus and Methods for Measurement and Interpretation of the Angular Variation of Light Scattering; Preliminary Results on Polystyrene Solutions
TL;DR: In this article, a photoelectric apparatus for the measurement of the angular dependence of light scattering from solutions is described and its performance is discussed, and methods of calculation for the determination of the average extension of the scattering molecules from the data are described.
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