Journal Article10.1039/d2np00083k
Marine natural products.
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TL;DR: A review of the literature published in 2020 for marine natural products (MNPs), with 757 citations (747 for the period January to December 2020) referring to compounds isolated from marine microorganisms and phytoplankton, green, brown and red algae, sponges, cnidarians, bryozoans, molluscs, tunicates, echinoderms, mangroves and other intertidal plants and microorganisms as discussed by the authors .
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About: This article is published in Natural Product Reports. The article was published on 14 Feb 2023. The article focuses on the topics: Medicine & Natural (archaeology).
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Citations
An overview on the nutritional and bioactive components of green seaweeds
TL;DR: In this article , the main nutrients and active substances present in different green seaweeds and their applications for high value utilization are discussed, and a review of their biological activities is provided.
Marine natural products.
Anthony R. Carroll,Brent R. Copp,Tanja Grkovic,Robert A. Keyzers,Michèle R. Prinsep +4 more
- 29 Jan 2024
TL;DR: This review summarizes 1411 newly discovered marine natural products (MNPs), highlighting their structural diversity, with a focus on the cyanobacterial metabolite lezoside, and providing insights into their potential applications and future research directions.
37
Study of marine microorganism metabolites: new resources for bioactive natural products
Noora Barzkar,Stanislav Sukhikh,Olga Babich +2 more
TL;DR: This review aims to analyze and summarize modern literature data on the biotechnological potential of marine fungi and bacteria as producers of a wide range of practically valuable products (surfactants, glyco-and lipopeptides, exopolysaccharides, enzymes, and metabolites with different biological activities: antimicrobial, antitumor, and cytotoxic).
22
Penicopeptide A (PPA) from the deep-sea-derived fungus promotes osteoblast-mediated bone formation and alleviates ovariectomy-induced bone loss by activating the AKT/GSK-3β/β-catenin signaling pathway
Yu-Ting Yue,Guang-Rong Ji,Xian-Wen Yang +2 more
TL;DR: In vitro and in vivo results demonstrated that PPA could promote osteoblast-related bone formation via the AKT, GSK-3β, and β-catenin signaling pathways, indicating the clinical potential of PPA as a candidate compound for osteoporosis prevention.
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Jellyfish Peptide as an Alternative Source of Antioxidant
TL;DR: In this paper , the authors obtained jellyfish peptides (JPHT-2) through enzymatic hydrolysis of lyophilized jellyfish powder under optimal conditions and measured their antioxidant activity.
References
New Insights into the Type II Toxins from the Sea Anemone Heteractis crispa.
Rimma Kalina,Steve Peigneur,Elena Zelepuga,Pavel S. Dmitrenok,Aleksandra Kvetkina,Natalia Y. Kim,Elena Leychenko,Jan Tytgat,Kozlovskaya Emma P,Margarita Monastyrnaya,Irina Gladkikh +10 more
TL;DR: The data suggest that Heteractis toxins could be used as molecular tools for NaV channel studies or insecticides rather than as pharmacological agents.
18
Discovery, Pharmacological Characterisation and NMR Structure of the Novel µ-Conotoxin SxIIIC, a Potent and Irreversible NaV Channel Inhibitor
Kirsten L. McMahon,Hue N. T. Tran,Jennifer R. Deuis,Richard J. Lewis,Irina Vetter,Christina I. Schroeder,Christina I. Schroeder +6 more
TL;DR: NMR analysis reveals the structure of SxIIIC includes the characteristic α-helix seen in other µ-conotoxins, which is expected to provide insights into residues important for NaV channel pore blocker selectivity and subsequently important for chronic pain drug development.
18
Shimalactone Biosynthesis Involves Spontaneous Double Bicyclo-Ring Formation with 8π-6π Electrocyclization
Isao Fujii,Makoto Hashimoto,Makoto Hashimoto,Kaori Konishi,Akiko Unezawa,Haruka Sakuraba,Kenta Suzuki,Harue Tsushima,Miho Iwasaki,Satsuki Yoshida,Akane Kudo,Rina Fujita,Aika Hichiwa,Koharu Saito,Takashi Asano,Jun Ishikawa,Daigo Wakana,Yukihiro Goda,Ayumi Watanabe,Mamoru Watanabe,Yui Masumoto,Junichiro Kanazawa,Hajime Sato,Masanobu Uchiyama +23 more
TL;DR: In this article, Aspergillus oryzae and Saccharomyces cerevisiae transformants expressing ShmA and ShmB produced oxabicyclo-ring formation reactions from preshimalactone epoxide.
18
Hp-s1 Ganglioside Suppresses Proinflammatory Responses by Inhibiting MyD88-Dependent NF-κB and JNK/p38 MAPK Pathways in Lipopolysaccharide-Stimulated Microglial Cells.
TL;DR: Findings indicated that Hp-s1 alleviated LPS-induced proinflammatory responses in microglial cells by downregulating MyD88-mediated NF-κB and JNK/p38 MAPK signaling pathways, suggesting further evaluation as a new anti-neuroinflammatory drug.
18
Molecular Network and Culture Media Variation Reveal a Complex Metabolic Profile in Pantoea cf. eucrina D2 Associated with an Acidified Marine Sponge.
Giovanni Andrea Vitale,Martina Sciarretta,Chiara Cassiano,Carmine Buonocore,Carmen Festa,Valerio Mazzella,Laura Núñez Pons,Maria Valeria D'Auria,Donatella de Pascale +8 more
TL;DR: The Gram-negative Pantoea eucrina D2 was isolated from the marine sponge Chondrosia reniformis, influenced by CO2 emissions and lowered pH, and the production of unusual surfactins derivatives was reported for the first time from this genus.
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