Journal Article10.1039/d2np00083k
Marine natural products.
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TL;DR: A review of the literature published in 2020 for marine natural products (MNPs), with 757 citations (747 for the period January to December 2020) referring to compounds isolated from marine microorganisms and phytoplankton, green, brown and red algae, sponges, cnidarians, bryozoans, molluscs, tunicates, echinoderms, mangroves and other intertidal plants and microorganisms as discussed by the authors .
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About: This article is published in Natural Product Reports. The article was published on 14 Feb 2023. The article focuses on the topics: Medicine & Natural (archaeology).
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- 29 Jan 2024
TL;DR: This review summarizes 1411 newly discovered marine natural products (MNPs), highlighting their structural diversity, with a focus on the cyanobacterial metabolite lezoside, and providing insights into their potential applications and future research directions.
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Study of marine microorganism metabolites: new resources for bioactive natural products
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Penicopeptide A (PPA) from the deep-sea-derived fungus promotes osteoblast-mediated bone formation and alleviates ovariectomy-induced bone loss by activating the AKT/GSK-3β/β-catenin signaling pathway
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Jellyfish Peptide as an Alternative Source of Antioxidant
TL;DR: In this paper , the authors obtained jellyfish peptides (JPHT-2) through enzymatic hydrolysis of lyophilized jellyfish powder under optimal conditions and measured their antioxidant activity.
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Ying Ye,Lei Du,Xingwang Zhang,Sean A. Newmister,Morgan McCauley,Juan V. Alegre-Requena,Wei Zhang,Shuai Mu,Atsushi Minami,Amy E. Fraley,Maria L. Adrover-Castellano,Nolan Carney,Vikram V. Shende,Feifei Qi,Hideaki Oikawa,Hikaru Kato,Sachiko Tsukamoto,Robert S. Paton,Robert S. Paton,Robert M. Williams,Robert M. Williams,David H. Sherman,Shengying Li,Shengying Li +23 more
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TL;DR: The brevianamide A biosynthetic gene cluster from Penicillium brevicompactum NRRL 864 is identified and the metabolic pathway is elucidated, revealing BvnE to be an essential isomerase/semipinacolase that specifies the selective production of the natural product.
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How different are marine microbial natural products compared to their terrestrial counterparts?
01 Jan 2022
TL;DR: In this paper , a cluster analysis of chemical fingerprints and molecular scaffold analysis of 55 817 compounds reported from marine and terrestrial microorganisms, and marine macro-organisms showed that 76.7% of the compounds isolated from marine microorganisms are closely related to compounds identified from terrestrial micro organisms.
Deep-Sea Fungi Could Be the New Arsenal for Bioactive Molecules.
TL;DR: A brief review of the structure, biological activity, and distribution of secondary metabolites produced by deep-sea fungi in the last five years is made.
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Beyond peptide bond formation: the versatile role of condensation domains in natural product biosynthesis
TL;DR: A comprehensive overview of the multifaceted role of C domains in the biosynthesis of specialized metabolites in bacteria and fungi is presented and different perspectives are offered on how the exceptional functional versatility of C domain may be exploited for bioengineering approaches to expand the chemical diversity of nonribosomal peptides and other natural products.
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Marine endophytic fungal metabolites: A whole new world of pharmaceutical therapy exploration
TL;DR: The growing threat arises due to diseases such as cancer and the infections around the world leading to a critical requirement for novel and constructive compounds with unique ways of action capable of combating these deadly diseases as discussed by the authors.
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