Management Guidelines for Children with Thyroid Nodules and Differentiated Thyroid Cancer

TL;DR: This is the first study to identify a surgeon volume threshold (>25 total thyroidectomies/y) that is associated with improved patient outcomes and has implications for quality improvement, criteria for referral and reimbursement, and surgical education.

TL;DR: Recommendations are provided for genetic testing; prenatal management; and surveillance for DICER1-associated pulmonary, renal, gynecologic, thyroid, ophthalmologic, otolaryngologic, and central nervous system tumors and gastrointestinal polyps.

TL;DR: Recommendations on the management of thyroid cancer in adults and is based on the 2014 British Thyroid Association guidelines, which recommend that potentially resectable recurrent or persistent disease should be managed with surgery whenever possible.

TL;DR: A diagnostic algorithm is proposed for solid tumors to facilitate the identification of patients with TRK fusion cancer and is based on a combination of fluorescence in situ hybridization, next-generation sequencing, and immunohistochemistry assays.

TL;DR: The data suggest that dose adjustments are not generally required in children and teenagers undergoing rhTSH stimulation for RAI scanning or serum-stimulated thyroglobulin determinations.

TL;DR: It is concluded that, once metformin fails to reach an adequate glycemic control, GLP-1 receptor agonists can be a valid alternative, especially in obese type 2 diabetic patients, because of the minor risk of developing hypoglycemia and the positive effect on body weight.

TL;DR: 180HB is an effective discriminator of an adenoma and may be a useful marker of the events in late aldosterone synthesis, and potassium repletion with potassium chloride and/or spironolactone in patients with ald testosterone-producing adenomas decreased the 180HB:PAC ratio by decreasing 180HB and increasing PAC.

TL;DR: It is concluded that active acromegaly is characterized by profound disturbances of not only glucose but also lipid metabolism, which in theory may precipitate the increased mortality in this disease.