Journal Article10.1016/S0140-6736(09)61497-5
Maintenance pemetrexed plus best supportive care versus placebo plus best supportive care for non-small-cell lung cancer: a randomised, double-blind, phase 3 study
Tudor Ciuleanu,Thomas Brodowicz,Christoph C. Zielinski,Joo Hang Kim,Maciej Krzakowski,E. Laack,Yi-Long Wu,Isabel Bover,Stephen Begbie,Valentina Tzekova,Branka Cucevic,José Rodrigues Pereira,Sung Hyun Yang,Jayaprakash Madhavan,Katherine P. Sugarman,Patrick Peterson,William J. John,K. Krejcy,Chandra P. Belani +18 more
TL;DR: Maintenance therapy with pemetrexed is well tolerated and offers improved progression-free and overall survival compared with placebo in patients with advanced non-small-cell lung cancer.
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About: This article is published in The Lancet. The article was published on 24 Oct 2009. The article focuses on the topics: Pemetrexed & Survival rate.
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Citations
Pemetrexed-induced Sweet Syndrome: First case report in the medical literature.
Mustafa Korkmaz,Melek Karakurt Eryilmaz,Mustafa Karaagac,Aykut Demirkıran,Murat Araz,Mehmet Artac +5 more
TL;DR: A case of Sweet Syndrome caused by pemetrexed in metastatic lung adenocarcinoma, a rare inflammatory disease characterized by the sudden emergence of painful, edematous, and erythematous papules, plaques, or nodules on the skin, is presented.
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Management of lung cancer
Gayathri Anandappa,Sanjay Popat +1 more
TL;DR: Individual treatment plans should be based on the histological and molecular characteristics of the tumour as well as the stage of disease at diagnosis, performance status and co-morbidities.
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Prospective phase II study of cisplatin plus pemetrexed with maintenance of pemetrexed for advanced non-squamous cell non-small cell lung cancer in Japan
Kazuhiro Asami,Masaaki Kawahara,Tomonori Hirashima,Hidekazu Suzuki,Kyoichi Okishio,Naoki Omachi,Motohiro Tamiya,Akihiro Tamiya,Aya Hirooka,Keiko Nakao,Taisuke Tsuji,Shinji Atagi +11 more
TL;DR: A phase II study is presented that assessed the efficacy and safety of cisplatin plus pemetrexed as induction chemotherapy, followed by maintenance therapy with peterrexed in advanced NSCLC patients in Japan.
Quelles options pour la chimiothérapie de première ligne des CBNPC de stade IV
TL;DR: La prise en charge en premiere ligne de traitement des CBNPC de stade IV etait jusqu’a present guidee par les recommandations publiees par l’ASCO en 2003, cependant, en cinq ans, de nouvelles molecules sont venues enrichir nos possibilites therapeutiques, and de nnewvelles notions bousculent nos standards.
3
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