Book Chapter10.1007/978-1-59745-290-8_8
Machine-Learning Techniques
Rob Sullivan
- 01 Jan 2012
- pp 363-454
132
TL;DR: These two broad classifications of machine-learning methods will ground us as the authors discuss a broad range of techniques and where they are currently being applied in life sciences research, expanding their toolkit and enabling us to take a very different path in their analysis efforts.
read more
Abstract: Our ultimate objective in data mining is to identify any hidden patterns or relationships between our data elements, and in one sense, machine learning provides us with a set of techniques to do just that: techniques that allow us to learn the patterns without any outside influence (unsupervised learning). However, just as is the case with anything, that power comes at a price, but the results can be very interesting and very significant. In other cases, we have some sense on what the results should be and so can guide the learning techniques through an initial “training” phase, directing our system and honing the results (supervised learning). These two broad classifications of machine-learning methods will ground us as we discuss a broad range of techniques and where they are currently being applied in life sciences research, expanding our toolkit and enabling us to take a very different path in our analysis efforts: using an artificial intelligence discipline and letting the data tell us what it contains. As datasets grow, these techniques become more important.
read more
Chat with Paper
AI Agents for this Paper
Find similar papers on Google Scholar, PubMed and Arxiv
Write a critical review of this paper
Analyze citations of this paper to find unaddressed research gaps
Citations
Molecular Breeding Strategy and Challenges Towards Improvement of Blast Disease Resistance in Rice Crop
Sadegh Ashkani,Mohd Y. Rafii,Mahmoodreza Shabanimofrad,Gous Miah,Mahbod Sahebi,Parisa Azizi,Fatah A. Tanweer,Mohd Sayeed Akhtar,Abbas Nasehi +8 more
TL;DR: This review includes examples of how advanced molecular method have been used in breeding programs for improving blast resistance, allowing rapid introgression of disease resistance genes into susceptible varieties as well as the incorporation of multiple genes into individual lines for more durable blast resistance.
Application of artificial intelligence models and optimization algorithms in plant cell and tissue culture
TL;DR: Artificial intelligence models and optimization algorithms can be considered a novel and reliable computational method in plant tissue culture.
166
A New Ensemble-Based Intrusion Detection System for Internet of Things
Adeel Abbas,Muazzam A. Khan,Muazzam A. Khan,Shahid Latif,Maria Ajaz,Awais Aziz Shah,Jawad Ahmad +6 more
TL;DR: An ensemble-based intrusion detection model that combines logistic regression, naive Bayes, and decision tree have been deployed with voting classifier after analyzing model’s performance with some prominent existing state-of-the-art techniques and results illustrate significant improvement in terms of accuracy as compared to existing models.
Combining hyper-resolution land surface modeling with SMAP brightness temperatures to obtain 30-m soil moisture estimates
Noemi Vergopolan,Nathaniel W. Chaney,Hylke E. Beck,Ming Pan,Justin Sheffield,Steven Chan,Eric F. Wood +6 more
TL;DR: In this paper, the authors presented a merging framework that combines a hyper-resolution land surface model (LSM), a radiative transfer model (RTM), and a Bayesian scheme to merge and downscale coarse resolution remotely sensed hydrological variables to a 30m spatial resolution.
121
Support vector regression optimized by meta-heuristic algorithms for daily streamflow prediction
TL;DR: Support vector regression was optimized by six meta-heuristic algorithms to predict daily streamflow in Naula watershed, State of Uttarakhand, India and it was demonstrated that SVR-HHO during calibration/validation periods had superior performance to the other meta- heuristic algorithms in terms of prediction accuracy.
119
References
Frank Rosenblatt: Principles of Neurodynamics: Perceptrons and the Theory of Brain Mechanisms
C. Van Der Malsburg
- 01 Jan 1986
TL;DR: In this paper, Rosenblatt formulates a series of machines, each of which serves to introduce a new concept, and each machine serves to describe a machine, the perceptron, but rather to put forward a theory.
332
Kavosh: a new algorithm for finding network motifs
Zahra Razaghi Moghadam Kashani,Hayedeh Ahrabian,Elahe Elahi,Abbas Nowzari-Dalini,Elnaz Saberi Ansari,Sahar Asadi,Shahin Mohammadi,Falk Schreiber,Falk Schreiber,Ali Masoudi-Nejad +9 more
TL;DR: A new algorithm, Kavosh, for finding k-size network motifs with less memory and CPU time in comparison to other existing algorithms, based on counting all k- size sub-graphs of a given graph (directed or undirected).
Topological generalizations of network motifs.
TL;DR: Using mathematical modeling, a systematic approach is presented to define "motif generalizations": families of motifs of different sizes that share a common architectural theme in transcription, neuronal, and electronic networks.
Convergent evolution of gene circuits
Gavin C. Conant,Andreas Wagner +1 more
TL;DR: It is shown that multiple types of transcriptional regulation circuitry in Escherichia coli and the yeast Saccharomyces cerevisiae have evolved independently and not by duplication of one or a few ancestral circuits.
217
MODA: An efficient algorithm for network motif discovery in biological networks
TL;DR: This paper presents a new algorithm (MODA) that incorporates techniques such as a pattern growth approach for extracting larger motifs efficiently and is able to identifylarger motifs with more than 8 nodes more efficiently than most of the current state-of-the-art motif discovery algorithms.
Related Papers (5)
Y. Yang
- 20 Nov 2018
Michael N. Johnstone,Matthew Peacock +1 more
- 01 Jan 2020
Rob Sullivan
- 01 Jan 2012