Loss of olfactory function leads to a decrease of trigeminal sensitivity
TL;DR: Amplitudes of chemo-somatosensory event-related potentials in response to suprathreshold trigeminal stimuli (CO2) were found to be smaller in patients indicating a decrease of trigeminally mediated sensations.
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Abstract: Healthy controls were compared to patients with decreased olfactory sensitivity (n = 32) to investigate interactions between the olfactory and trigeminal systems. Amplitudes of chemo-somatosensory event-related potentials in response to suprathreshold trigeminal stimuli (CO 2 ) were found to be smaller in patients (P < 0.05) indicating a decrease of trigeminally mediated sensations.
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Citations
Effects of olfactory function, age, and gender on trigeminally mediated sensations: a study based on the lateralization of chemosensory stimuli
TL;DR: Results of the present study indicate that patients with olfactory dysfunction have lower trigeminal sensitivity compared with normosmic controls, which seems to be independent of the cause ofOlfactory loss.
213
Intranasal chemosensory function of the trigeminal nerve and aspects of its relation to olfaction.
Thomas Hummel,Andrew Livermore +1 more
TL;DR: The interaction between the olfactory and trigeminal systems is not straightforward and may be difficult to predict, but it has a powerful influence on the perception of odors.
205
Assessment of upper respiratory tract and ocular irritative effects of volatile chemicals in humans.
Richard L. Doty,J. Enrique Cometto-Muñiz,Alfredo A. Jalowayski,Pamela Dalton,Martin Kendal-Reed,Michael Hodgson +5 more
TL;DR: A major goal of this compendium is to inform the reader of procedures for assessing irritation in humans and to provide information of value in the continued interpretation and development of empirical databases upon which future reasoned regulatory health decisions can be made.
Crossmodal plasticity in sensory loss.
TL;DR: A wide range of studies showing that sensory loss may lead, depending of the affected sensory system, to functional changes in other, primarily not affected senses, which range from heightened to lowered abilities are summarized.
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TL;DR: In this paper, the authors evaluated a dual threshold/odor identification test administered in the CCCRC and by the self-administered University of Pennsylvania Smell Identification Test (UPSIT), with a correlation coefficient of 0.92.
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