Long-Term Decrease in Bladder Cancer Recurrence with Hexaminolevulinate Enabled Fluorescence Cystoscopy
H. Barton Grossman,Arnulf Stenzl,Yves Fradet,Lance A. Mynderse,Martin Kriegmair,J. Alfred Witjes,Mark S. Soloway,Alexander Karl,Maximilian Burger +8 more
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TL;DR: Hexaminolevulinate fluorescence cystoscopic detection of papillary, nonmuscle invasive bladder cancer significantly improves long-term bladder cancer time to recurrence with a trend toward improved bladder preservation.
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About: This article is published in The Journal of Urology. The article was published on 01 Jul 2012. and is currently open access. The article focuses on the topics: Bladder cancer & Cystoscopy.
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Citations
EAU Guidelines on Non–Muscle-invasive Urothelial Carcinoma of the Bladder: Update 2013
Marko Babjuk,Maximilian Burger,Richard Zigeuner,Shahrokh F. Shariat,Bas W.G. van Rhijn,Eva Comperat,Richard Sylvester,Eero Kaasinen,Andreas Böhle,Joan Palou Redorta,Morgan Rouprêt +10 more
TL;DR: The European Association of Urology (EAU) guidelines on non-muscle-invasive bladder cancer (NMIBC) were published in 2013 and the levels of evidence and grades of recommendation were assigned.
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The Economics of Bladder Cancer: Costs and Considerations of Caring for This Disease
Robert S. Svatek,Brent K. Hollenbeck,Sten Holmäng,Richard K. Lee,Simon P. Kim,Arnulf Stenzl,Yair Lotan +6 more
TL;DR: Regardless of disease severity, improvements in the efficiency of bladder cancer care to limit unnecessary interventions and optimize effective cancer treatment can reduce overall health care costs.
501
Latest developments in molecular tracers for fluorescence image-guided cancer surgery
TL;DR: Preclinical and clinical evidence, ongoing clinical trials, and the latest developments in the field of molecular near-infrared tracers for fluorescence-guided cancer surgery are discussed.
383
Effect of Intravesical Instillation of Gemcitabine vs Saline Immediately Following Resection of Suspected Low-Grade Non-Muscle-Invasive Bladder Cancer on Tumor Recurrence: SWOG S0337 Randomized Clinical Trial.
Edward M. Messing,Catherine M. Tangen,Seth P. Lerner,Deepak M. Sahasrabudhe,Theresa M. Koppie,David P. Wood,Philip C. Mack,Robert S. Svatek,Christopher P. Evans,Khaled S. Hafez,Daniel J. Culkin,Timothy C. Brand,Lawrence Karsh,Jeffrey M. Holzbeierlein,Shandra Wilson,Guan Wu,Melissa Plets,Nicholas J. Vogelzang,Ian M. Thompson +18 more
TL;DR: Among patients with suspected low-grade non–muscle-invasive urothelial cancer, immediate postresection intravesical instillation of gemcitabine, compared withinstillation of saline, significantly reduced the risk of recurrence over a median of 4.0 years.
ICUD-EAU International Consultation on Bladder Cancer 2012: Non-muscle-invasive urothelial carcinoma of the bladder.
Maximilian Burger,Willem Oosterlinck,Badrinath R. Konety,Sam S. Chang,Sigurdur Gudjonsson,Raj S. Pruthi,Mark S. Soloway,Eduardo Solsona,Paul Sved,Marko Babjuk,Maurizio Brausi,Christopher Cheng,Eva Comperat,Colin P.N. Dinney,Wolfgang Otto,Jay B. Shah,Joachim Thürof,J. Alfred Witjes +17 more
TL;DR: A summary of the Second International Consultation on Bladder Cancer recommendations on the diagnosis and treatment options for non-muscle-invasive urothelial cancer of the bladder (NMIBC) using an evidence-based approach is presented.
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References
Improved detection and treatment of bladder cancer using hexaminolevulinate imaging: a prospective, phase iii multicenter study
Dieter Jocham,Fred Witjes,Sigrid Wagner,Bram Zeylemaker,Jeroen Van Moorselaar,Marc-Oliver Grimm,Rolf Muschter,Gralf Popken,F. König,Ruth KNüCHEL,Karl-Heinz Kurth +10 more
TL;DR: HAL imaging is more effective than standard white light cystoscopy for detecting bladder tumors and lesions and leads to improved treatment in a significant number of patients (p <0.0001).
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Hexaminolevulinate Guided Fluorescence Cystoscopy Reduces Recurrence in Patients With Nonmuscle Invasive Bladder Cancer
Arnulf Stenzl,Maximilian Burger,Yves Fradet,Lance A. Mynderse,Mark S. Soloway,J. Alfred Witjes,Martin Kriegmair,Alexander Karl,Yu Shen,H. Barton Grossman +9 more
TL;DR: Hexaminolevulinate fluorescence cystoscopy significantly improves the detection of Ta and T1 lesions and significantly reduces the rate of tumor recurrence at 9 months.
294
Hexyl Aminolevulinate Fluorescence Cystoscopy: A New Diagnostic Tool for Photodiagnosis of Superficial Bladder Cancer—A multicenter study
Patrice Jichlinski,Louis Guillou,Steinar J. Karlsen,Per-Uno Malmström,Dieter Jocham,Bjørn Brennhovd,Eva Johansson,Thomas Gärtner,Norbert Lange,Hubert van den Bergh,Hans-Jürg Leisinger +10 more
TL;DR: HAL fluorescence cystoscopy is a new, sensitive, promising diagnostic procedure that showed improved detection of bladder tumors, in particular CIS.
273
Long-term benefit of 5-aminolevulinic acid fluorescence assisted transurethral resection of superficial bladder cancer: 5-year results of a prospective randomized study
Dmitry I. Daniltchenko,Claus R. Riedl,Markus Sachs,Frank Koenig,Kurosch L. Daha,Heinz Pflueger,Stefan A. Loening,D. Schnorr +7 more
TL;DR: The initial advantage of improved tumor detection and decreased recurrence rates by ALA fluorescence assisted TUR is maintained for years, and effectively reduces morbidity and costs in patients with superficial bladder tumors.
197
5-aminolaevulinic acid-induced fluorescence cystoscopy during transurethral resection reduces the risk of recurrence in stage Ta/T1 bladder cancer
TL;DR: To assess the influence of 5‐aminolaevulinic acid‐induced fluorescence cystoscopy during transurethral resection (TUR) on the recurrence rate and the length of tumour‐free interval in stage Ta/T1 transitional cell carcinoma (TCC) of the urinary bladder, FC is used.
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