Journal Article10.1152/JN.1997.77.3.1155
Localization of the Spinal Network Associated With Generation of Hindlimb Locomotion in the Neonatal Rat and Organization of Its Transverse Coupling System
E. Kremer,Aharon Lev-Tov +1 more
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TL;DR: The segmental organization of the hindlimb locomotor pattern generators and the coordination of rhythmic motor activity were studied in isolated spinal cords of the neonatal rat and indicated that the transverse coupling system in the caudal-thoracic and lumbar segments in specialized and that left-right alternation in the lumbr cord can be carried out by the cross connectivity.
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Abstract: Kremer, E. and A. Lev-Tov. Localization of the spinal network associated with generation of hindlimb locomotion in the neonatal rat and organization of its transverse coupling system. J. Neurophysi...
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Citations
Motoneurons regulate the central pattern generator during drug-induced locomotor-like activity in the neonatal mouse.
TL;DR: It is concluded that motoneurons provide feedback to the central pattern generator (CPG) during drug-induced locomotor-like activity.
Organization of left–right coordination in the mammalian locomotor network
TL;DR: The present understanding of commissural pathways in the functioning of spinal cord central pattern generators (CPGs) is described and the means by which reciprocal inhibition and integration of sensory information are maintained in swimming vertebrates is described.
Neural development of the zebrafish (Danio rerio) pectoral fin
Dean H. Thorsen,Melina E. Hale +1 more
TL;DR: The pattern of larval fin innervation recorded is associated with later muscle subdivision, suggesting that fin muscles may be functionally subdivided before they are morphologically subdivided.
Locomotor-Related Networks in the Lumbosacral Enlargement of the Adult Spinal Cat: Activation Through Intraspinal Microstimulation
Lisa Guevremont,C.G. Renzi,Jonathan A. Norton,Jan Kowalczewski,Rajiv Saigal,Vivian K. Mushahwar +5 more
- 18 Sep 2006
TL;DR: Investigation of the use of low-level tonic intraspinal microstimulation as a means of activating spinal locomotor networks in adult cats with complete spinal transections found it more effective in eliciting alternating movements in the hindlimbs than stimulation in the rostral regions.
Contribution of commissural projections to bulbospinal activation of locomotion in the in vitro neonatal rat spinal cord.
TL;DR: Results suggest that locomotor-related commissural projections are redundantly distributed along a bi-directional gradient that centers on the thoracolumbar junction, which not only provides a robust left-right coordinating mechanism but also supports locomotor rhythm generation in response to brain stem stimulation.
References
The neuronal correlate of locomotion in fish. "Fictive swimming" induced in an in vitro preparation of the lamprey spinal cord.
A. H. Cohen,Peter Wallén +1 more
TL;DR: In this article, an in vitro preparation of the lamprey spinal cord was developed to enable detailed studies of the neuronal organization of the central spinal network generating fish swimming movements, one basic type of vertebrate locomotion.
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Cellular mechanisms underlying modulation of breathing pattern in mammals.
Jack L. Feldman,Jeffrey C. Smith +1 more
TL;DR: Using a novel experimental in vitro system, several classes of cellular mechanisms difficult or impossible to study in vivo or in tissue slices are investigated and conclusions and hypotheses are made that greatly enhance understanding of the nervous control of respiration.
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Effects of inhibitory amino acid antagonists on reciprocal inhibitory interactions during rhythmic motor activity in the in vitro neonatal rat spinal cord
TL;DR: Addition of the GABAA receptor antagonist bicuculline, or the glycine receptor antagonist strychnine, transformed alternating flexor-extensor and left-right activity into patterns characterized by bilaterally synchronous rhythmic activation of all hindlimb ENGs.
200
Strychnine eliminates alternating motor output during fictive locomotion in the lamprey
TL;DR: The result suggests that temporal bursting on the right and left sides of the spinal cord is generated by independent neuronal oscillators, while the alternation between the two sides results from crossed inhibitory coupling between these oscillators.
165
Spontaneous rhythmic bursts induced by pharmacological block of inhibition in lumbar motoneurons of the neonatal rat spinal cord
TL;DR: Results show that in the rat spinal cord highly patterned motor output can occur despite block of inhibition, and Rhythmic bursts appear to result from large, synchronous synaptic events generated by a network modulated by 5-HT and highly sensitive to variations in efficacy of glutamatergic synaptic transmission.
155