Journal Article10.1148/RADIOLOGY.219.2.R01MA20432
Local recurrence after radical prostatectomy : Correlation of US features with prostatic fossa biopsy findings
154
TL;DR: Transrectal US is more sensitive but less specific than digital rectal examination in the detection of local recurrence in patients with biochemical recurrence following radical prostatectomy.
read more
Abstract: PURPOSE: To evaluate the diagnostic accuracy of transrectal ultrasonography (US) in the detection of local recurrence following radical prostatectomy. MATERIALS AND METHODS: Ninety-nine patients with biochemical recurrence after radical prostatectomy were evaluated at transrectal US and prostatic fossa biopsy. Location of suspected recurrence at transrectal US and clinical features, such as prostate-specific antigen levels and digital rectal examination findings, were correlated with biopsy results. RESULTS: Forty-one (41%) of 99 cases of local recurrence were detected. The percentage of sites of lesions identified at transrectal US and corresponding positive biopsy rates were as follows: the urethrovesical anastomotic area, 56% and 61%; bladder neck, 26% and 54%; retrovesical space, 4% and 100%; and more than one site, 14% and 71%. By comparing transrectal US and digital rectal examination, the sensitivities were 76% and 44% (P = .007), while specificities were 67% and 91% (P = .004), respectively. An in...
read more
Chat with Paper
AI Agents for this Paper
Find similar papers on Google Scholar, PubMed and Arxiv
Write a critical review of this paper
Analyze citations of this paper to find unaddressed research gaps
Citations
Is there a role for 11C-choline PET/CT in the early detection of metastatic disease in surgically treated prostate cancer patients with a mild PSA increase <1.5 ng/ml?
Paolo Castellucci,Chiara Fuccio,Domenico Rubello,Riccardo Schiavina,Ivan Santi,Cristina Nanni,Vincenzo Allegri,Gian Carlo Montini,Valentina Ambrosini,Stefano Boschi,Giuseppe Martorana,Maria Cristina Marzola,Stefano Fanti +12 more
TL;DR: The aim of this study was to evaluate the potential usefulness of whole-body 11C-choline PET/CT in the re-staging of prostate cancer patients previously treated with radical prostatectomy who presented a mild increase of prostate-specific antigen (PSA) <1.5 ng/ml during follow-up (FU).
168
Anatomic boundaries of the clinical target volume (prostate bed) after radical prostatectomy
K. Wiltshire,Kristy K. Brock,Masoom A. Haider,Daniel R. Zwahlen,Daniel R. Zwahlen,Vickie Kong,Elisa K. Chan,Joanne Moseley,Andrew Bayley,Charles Catton,Peter Chung,Mary Gospodarowicz,Michael Milosevic,Andrew Kneebone,Padraig Warde,Cynthia Ménard +15 more
TL;DR: The CTV is larger than historically practiced at this institution and should be encompassed by a microscopic tumoricidal dose.
167
Imaging of prostate cancer local recurrences: why and how?
TL;DR: Recent advances in imaging may improve the outcome of salvage therapies (by improving patient selection and treatment targeting) and should open the way to focal salvage treatments in the near future.
159
Prostate cancer recurrence after radical prostatectomy: the role of 3-T diffusion imaging in multi-parametric magnetic resonance imaging
Valeria Panebianco,Flavio Barchetti,Alessandro Sciarra,Daniela Musio,Valerio Forte,Vincenzo Gentile,Vincenzo Tombolini,Carlo Catalano +7 more
TL;DR: Diffusion-weighted magnetic resonance imaging (DWI-MRI) is being increasingly used in oncology and can diagnose local prostate cancer recurrence after radical prostatectomy, while DWI-MR is almost comparable to DCE-MRI in detecting local recurrence.
147
Postoperative Radiation Therapy for Pathologically Advanced Prostate Cancer After Radical Prostatectomy
Andrew J. Stephenson,Michel Bolla,Alberto Briganti,Cesare Cozzarini,Judd W. Moul,Mack Roach,Hendrik Van Poppel,Anthony L. Zietman +7 more
TL;DR: Given the absence of data from randomized trials demonstrating superiority of one approach over the other in terms of quantity and quality of life, this work advocates multidisciplinary input and shared and informed decision making among patients, urologists, and radiation oncologists based on the relative advantages and disadvantages of each approach.
127
References
Cancer statistics, 1999.
TL;DR: The Surveillance Research Program of the American Cancer Society's Department of Epidemiology and Surveillance Research reports its 33rd annual compilation of cancer frequency, incidence, mortality, and survival data for the United States.
Natural history of progression after PSA elevation following radical prostatectomy.
Charles R. Pound,Alan W. Partin,Mario A. Eisenberger,Daniel W. Chan,Jay D. Pearson,Patrick C. Walsh +5 more
TL;DR: Several clinical parameters help predict the outcomes of men with PSA elevation after radical prostatectomy, and these data may be useful in the design of clinical trials, the identification of men for enrollment into experimental protocols, and counseling men regarding the timing of administration of adjuvant therapies.
3.1K
Correlation of pathologic findings with progression after radical retropubic prostatectomy.
TL;DR: This study was performed to evaluate the effect of positive margins, Gleason grade, and capsular penetration on progression after radical prostatectomy.
739
Prostate-specific Antigen After Anatomic Radical Retropubic Prostatectomy. Patterns of Recurrence and Cancer Control
TL;DR: Men undergoing RRP for clinically localized prostate cancer showed a 16% actuarial rate of development of metastatic disease at 10 years, considerably better than conservative therapy and justifies RRP as the treatment of choice for men with clinically localized disease who are otherwise healthy and have a greater than 10-year life expectancy.
600
Serum PSA after anatomic radical prostatectomy. The Johns Hopkins experience after 10 years
TL;DR: The long-term value of serum PSA as a measure of progression after anatomic radical prostatectomy is demonstrated and suggests that radiation therapy is not effective in sterilizing occult local residual tumor in many men.
592
Related Papers (5)
Andrew J. Stephenson,Shahrokh F. Shariat,Michael J. Zelefsky,Michael W. Kattan,E. Brian Butler,Bin S. Teh,Eric A. Klein,Patrick A. Kupelian,Claus G. Roehrborn,David A. Pistenmaa,Heather D. Pacholke,Stanley L. Liauw,Matthew S. Katz,Steven A. Leibel,Peter T. Scardino,Kevin M. Slawin,Kevin M. Slawin +16 more