Journal Article10.1016/S1461-5347(98)00007-8
Liposomes: quo vadis?
Gert Storm,Daan J.A. Crommelin +1 more
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TL;DR: Liposomes have matured as a delivery system for therapeutic agents, and the authors provide their perspective on where the field is going and where opportunities can be found for rational improvement of drug therapy with liposomes.
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About: This article is published in Pharmaceutical Science & Technology Today. The article was published on 01 Apr 1998.
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Citations
Olive Oil-Based Delivery of Photosensitizers for Bacterial Eradication
Faina Nakonechny,Yeshayahu Nitzan,Marina Nisnevitch +2 more
- 01 Feb 2012
TL;DR: Nisnevitch et al. as discussed by the authors used mechanochemical treatment of olive oil and titanium dioxide to create new solid-phase composite materials which combined useful properties of various components with a different nature.
•Dissertation
Liposomes:Formulation and characterisation as contrast agents and as vaccine delivery systems
Randip Kaur
- 01 May 2011
TL;DR: This research initially focused on the formulation of gas-filled lipid coated microbubbles and their potential activation of macrophages using in vitro models, and the proposed hypotheses for the mechanism behind the immunostimulatory effect obtained with DDA:TDB is the ‘depot effect’.
8
Microfluidic Fabrication of Vesicles
Ho Cheung Shum,Julian Thiele,Shin-Hyun Kim +2 more
- 01 Jan 2014
TL;DR: Current understanding behind different kinds of vesicle formation is introduced, conventional and microfluidic techniques for their formation are surveyed, new approaches of encapsulation and release of active ingredients in microfluidity vesicles are discussed, and future research and development in the area is pointed to.
A novel method to chemically bind thiazolidine-2,4-dione through cross-linked chitosan nanoparticles using malanodialdehyde as a cross-linker
SinghPrashant,SinghPrashant,KumariKamlesh,KumariKamlesh,TomarVartika,SamimMohd.,PatelRajan,MehrotraGopal Kumar,DubeyMonica,PandeyNarendra Deo,KatyalAnju +10 more
TL;DR: A novel method to chemically bind thiazolidine-2,4-dione through cross-linked chitosan nanoparticles using malanodialdehyde as a new cross-linker and well characterized by FT-IR, NMR, TGA, DSC, powder X-ray diff...
8
Insertion of semifluorinated diblocks on DMPC and DPPC liposomes. Influence on the gel and liquid states of the bilayer
Juan Sabín,Gerardo Prieto,Joan Estelrich,Félix Sarmiento,Miguel Costas +4 more
- 15 Aug 2010
TL;DR: Differential Scanning Calorimetry was used to study the effect of the incorporation of a series of semifluorinated diblocks on the gel and liquid states of the bilayer of large multilamellar DMPC and DPPC liposomes, and traces suggest that the structure of the fluorinated liposome is a double bilayer at 3:4 and 1:2 and a trilayer at 2:1 lipid/F(n)H(m)
7
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Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors.
TL;DR: By selective changes in lipid composition, up to a 60-fold increase in the fraction of recovered dose present in blood 24 hr after i.v. injection is achieved, which has considerable therapeutic potential in cancer for increasing the concentration of cytotoxic agents in tumors while minimizing the likelihood of toxicity to the reticuloendothelial system.
Surface modification of nanoparticles to oppose uptake by the mononuclear phagocyte system
TL;DR: The literature reviewed provides enough promise for anticipating therapeutic and diagnostic applications of surface-modified nanoparticles, with particular focus on the literature concerning particles other than liposomes.
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Specific targeting with poly(ethylene glycol)-modified liposomes: coupling of homing devices to the ends of the polymeric chains combines effective target binding with long circulation times
Gabriele Blume,Gregor Cevc,M.D.J.A. Crommelin,Irma A. J. M. Bakker-Woudenberg,C. Kluft,Gert Storm +5 more
TL;DR: It is shown that the PEG-modified liposomes with such a homing device coupled to the ends of the long PEG chains may combine long vesicle circulation times in the blood with high target binding capability.
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Liposomes as drug carriers : recent trends and progress
Gregory Gregoriadis
- 01 Jan 1988
TL;DR: This book is a substantial update and expansion of a previous volume edited by Gregoriadis and Allinson in 1980 and discusses applications related to antimicrobial and cancer therapy, vaccines, enzyme therapy, metal detoxification and diagnostics.
331
Liposomes in gene therapy
Danilo D. Lasic,N.S. Templeton +1 more
TL;DR: In this paper, DNA complexation with cationic polymers was used to coat DNA and then DNA recombination was performed to improve gene expression and to improve specific DNA sequences.
270