Light Emitting Diode (LED) Phototherapy versus Conventional Phototherapy in Neonatal Hyperbilirubinemia: A Single Blinded Randomized Control Trial from Coastal India.
Sreesravya Gutta,Janardhan Shenoy,Sowmini P. Kamath,Prasanna Mithra,B. Shantharam Baliga,Muralikeshava Sarpangala,Mukund P. Srinivasan +6 more
TL;DR: The rates of decrease in total serum bilirubin levels and increase in urinary lumirUBin levels were significant with LED when compared with conventional phototherapy, implying LED to be more efficacious.
read more
Abstract: Neonatal hyperbilirubinemia is a common problem with potentiality to cause irreversible brain damage. Reduction of serum bilirubin level is essential to minimize such damage. Compact fluorescent tubes, halogen bulbs, fiber optic blankets, and LEDs are commonly used light sources for phototherapy with varying efficacies. This study aimed at evaluating the effect of LED versus conventional phototherapy on (a) rate of reduction in total serum bilirubin levels, (b) effect on urinary lumirubin excretion, and (c) comparing side effects of phototherapies among neonates with hyperbilirubinemia. In this randomized control trial, 166 neonates ≥ 35 weeks of age requiring phototherapy were recruited and further divided into 2 groups [LED (83) and conventional (83)] by using computer generated random numbers. Serial total serum bilirubin levels and random urinary lumirubin levels were collected and side effects of phototherapy were noted. Rate of fall in total serum bilirubin levels (TSB, μmol/L/hour) and random urinary lumirubin levels were computed. Data were collected using a pretested proforma. Analysis was done with Statistical Package for Social Sciences (SPSS) version 11.5. Independent sample "t" test and Chi-square tests were used with p value of <0.05 being significant. Significant difference was documented in mean rate of decrease of TSB (μmol/L/hour) in LED group (5.3 ± 2.91) when compared to conventional group (3.76 ± 2.39) (p <0.001). A significant increase in mean random urinary lumirubin levels (arbitrary units) was observed in LED group (129.01 ± 33.18) when compared to conventional group (114.44 ± 44.84) (p = 0.021). Side effects were minimal and comparable in both groups. This study concludes the rates of decrease in total serum bilirubin levels and increase in urinary lumirubin levels were significant with LED when compared with conventional phototherapy, implying LED to be more efficacious.
read more
Chat with Paper
AI Agents for this Paper
Find similar papers on Google Scholar, PubMed and Arxiv
Write a critical review of this paper
Analyze citations of this paper to find unaddressed research gaps
Citations
Manufacturing Multicolor LED-Based Phototherapy Device with a Novel 3D Design
Busra Yasar,Yalcin Isler,Nermin Topaloglu Avsar +2 more
TL;DR: Researchers designed a novel 3D phototherapy device with 3 foldable LED panels and high-voltage blue-green white LEDs to treat newborn jaundice, minimizing risks of nausea and dizziness, and incorporating automatic temperature and light intensity sensors for user safety.
References
Management of Hyperbilirubinemia in the Newborn Infant 35 or More Weeks of Gestation
TL;DR: These guidelines provide a framework for the prevention and management of hyperbilirubinemia in newborn infants of 35 or more weeks of gestation and recommend that clinicians promote and support successful breastfeeding and treat newborns with phototherapy or exchange transfusion to prevent the development of severe hyperbil Kirubin encephalopathy.
Phototherapy to prevent severe neonatal hyperbilirubinemia in the newborn infant 35 or more weeks of gestation.
Vinod K. Bhutani,Newborn +1 more
TL;DR: To standardize the use of phototherapy consistent with the American Academy of Pediatrics clinical practice guideline for the management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation, phototherapy devices currently marketed in the United States that incorporate fluorescent, halogen, fiber-optic, or blue light-emitting diode light sources were assessed.
197
A new blue light-emitting phototherapy device: a prospective randomized controlled study.
Daniel S. Seidman,Jonathan Moise,Jonathan Moise,Jonathan Moise,Zivanit Ergaz,Zivanit Ergaz,Zivanit Ergaz,Arie Laor,Arie Laor,Arie Laor,Hendrik J. Vreman,Hendrik J. Vreman,Hendrik J. Vreman,David K. Stevenson,David K. Stevenson,David K. Stevenson,Rena Gale,Rena Gale,Rena Gale +18 more
TL;DR: The blue gallium nitride LED device is as effective as conventional phototherapy and is readily accepted by nursing staff, and offer a new highly versatile approach to the treatment of jaundice.
100
A prospective randomized controlled study of phototherapy using blue and blue-green light-emitting devices, and conventional halogen-quartz phototherapy.
Daniel S. Seidman,Jonathan Moise,Zivanit Ergaz,Arie Laor,Hendrik J. Vreman,David K. Stevenson,Rena Gale +6 more
TL;DR: There was no statistically significant difference in the effectiveness of phototherapy using blue-green LEDs, blue LEDs or conventional halogen-quartz bulbs when using low light irradiance.
96