Open Access
KDIGO Clinical Practice Guideline for Glomerulonephritis
Kai-Uwe Eckardt,Bertram L. Kasiske +1 more
- 01 Jan 2012
Vol. 2, Iss: 2
987
TL;DR: This chapter discusses general principles in the management of glomerular disease, as well as methods for guideline development and examples of successful implementation of these principles.
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Abstract: 142 Summary of Recommendation Statements 143 Chapter 1: Introduction 154 Chapter 2: General principles in the management of glomerular disease 156 Chapter 3: Steroid-sensitive nephrotic syndrome in children 163 Chapter 4: Steroid-resistant nephrotic syndrome in children 172 Chapter 5: Minimal-change disease in adults 177 Chapter 6: Idiopathic focal segmental glomerulosclerosis in adults 181 Chapter 7: Idiopathic membranous nephropathy 186 Chapter 8: Idiopathic membranoproliferative glomerulonephritis 198 Chapter 9: Infection-related glomerulonephritis 200 Chapter 10: Immunoglobulin A nephropathy 209 Chapter 11: Henoch-Schönlein purpura nephritis 218 Chapter 12: Lupus nephritis 221 Chapter 13: Pauci-immune focal and segmental necrotizing glomerulonephritis 233 Chapter 14: Anti-glomerular basement membrane antibody glomerulonephritis 240 Methods for guideline development 243 Biographic and Disclosure Information 252
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Citations
KDIGO 2021 Clinical Practice Guideline for the Management of Glomerular Diseases
Brad H. Rovin,Sharon G. Adler,Jonathan Barratt,Frank Bridoux,Kelly A. Burdge,Tak Mao Chan,H. Terence Cook,Fernando C. Fervenza,Keisha L. Gibson,Richard J. Glassock,David Jayne,Vivekanand Jha,Adrian Liew,Zhihong Liu,Juan M. Mejia-Vilet,Carla M. Nester,Jai Radhakrishnan,Elizabeth M. Rave,Heather N. Reich,Pierre Ronco,Jan-Stephan F. Sanders,Sanjeev Sethi,Yusuke Suzuki,Sydney C.W. Tang,Vladimir Tesar,Marina Vivarelli,Jack F.M. Wetzels,Jürgen Floege +27 more
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Summary of KDIGO 2012 CKD Guideline: behind the scenes, need for guidance, and a framework for moving forward
Adeera Levin,Paul E. Stevens +1 more
TL;DR: The 2012 KDIGO Guideline for CKD evaluation, classification, and management has updated the original 2002 KDOQI Guidelines, using newer data and addressing issues raised over the last decade concerning definitions and assessment.
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Focal Segmental Glomerulosclerosis
Avi Z. Rosenberg,Jeffrey B. Kopp +1 more
TL;DR: Important outstanding issues remain, including the identity of the plasma factor believed to be responsible for primary FSGS, the value of routine implementation of genetic testing, and the identification of more effective and less toxic therapeutic interventions for FSGS.
References
Methylprednisolone plus Chlorambucil as Compared with Methylprednisolone Alone for the Treatment of Idiopathic Membranous Nephropathy
TL;DR: In patients with the nephrotic syndrome caused by idiopathic membranous nephropathy, treatment with methylprednisolone and chlorambucil for six months induces an earlier remission of the nePhrotic Syndrome than methylpredisonsolone alone, but the difference may diminish with time.
Clinical and epidemiological assessment of steroid-resistant nephrotic syndrome associated with the NPHS2 R229Q variant
Eduardo Machuca,Eduardo Machuca,Aurélie Hummel,Aurélie Hummel,Fabien Nevo,Jacques Dantal,Frank Martinez,Essam Al-Sabban,Véronique Baudouin,Laurent Abel,Laurent Abel,Jean-Pierre Grünfeld,Jean-Pierre Grünfeld,Corinne Antignac,Corinne Antignac +14 more
TL;DR: This study shows that compound heterozygosity for p.R229Q is associated with adult-onset steroid-resistant NS, mostly among patients of European and South American origin and Screening for the p.
Controlled trial of cyclophosphamide in idiopathic membranous nephropathy.
TL;DR: It is concluded that treatment with cyclophosphamide for one year did not have a favorable effect on proteinuria, renal function or morphologic aspects of the glomerular lesion.
A Randomized Pilot Trial Comparing Cyclosporine and Azathioprine for Maintenance Therapy in Diffuse Lupus Nephritis over Four Years
Gabriella Moroni,Andrea Doria,Marta Mosca,Ornella Della Casa Alberighi,Gianfranco Ferraccioli,Silvano Todesco,Carlo Manno,Paolo Altieri,Roberto Ferrara,Simona Greco,Claudio Ponticelli +10 more
TL;DR: For patients with diffuse proliferative lupus nephritis, azathioprine or cyclosporine combined with corticosteroids demonstrated equal efficacy in the prevention of flares.
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