Book Chapter10.3109/9780203089736-6
Is There Evidence for Cardiogenic Stem Cells Outside the Heart in Adult Mammals
Elina Minami,Charles E. Murry,Hans Reinecke +2 more
- 10 Dec 2007
- pp 37-52
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About: The article was published on 10 Dec 2007. The article focuses on the topics: Stem cell.
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Citations
Delivering stem cells to the heart in a collagen matrix reduces relocation of cells to other organs as assessed by nanoparticle technology
TL;DR: Collagen matrix as a delivery vehicle significantly reduced the relocation of transplanted MSCs to remote organs and noninfarcted myocardium and failed to improve cardiac function.
Collagen-cellulose composite thin films that mimic soft-tissue and allow stem-cell orientation.
Terry W. J. Steele,Charlotte L. Huang,Evelyne Bao-Vi Nguyen,Udi Sarig,Udi Sarig,Saranya Kumar,Effendi Widjaja,Joachim Say Chye Loo,Marcelle Machluf,Freddy Yin Chiang Boey,Zlata Vukadinovic,Andreas Hilfiker,Subbu S. Venkatraman +12 more
TL;DR: A collagen–cellulose composite film (CCCF) compared against swine small intestine submucosa in regards to mechanical properties, cell growth, and histological analysis, and Mesenchymal stem cells, human umbilical vein endothelial cells, and human coronary artery smooth muscle cells were able to proliferate on the collagen films with specific cell orientation.
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•Journal Article
Bone marrow-derived regenerated cardiomyocytes (CMG cells) express functional adrenergic and muscarinic receptors
Daihiko Hakuno,Yuichi Tomita,Tomohiro Manabe,Yusuke Suzuki,Fusako Konishi,Eiichi Takahashi,Jun Fujita,Isao Shibuya,Haruko Kawaguchi,Shinji Makino,Satoshi Ogawa,Keiichi Fukuda +11 more
TL;DR: In this article, the authors investigated whether these receptors are expressed in differentiated CMG cells, and if so, whether they have downstream signaling systems, and they found that CMG-cells had already expressed &agr;1A-, &agrg;1B-, and &aggr; 1D-adrenergic receptor mRNA before 5-azacytidine treatment, whereas expression of &bgr;1-, &graham;1, &braham;2, &ggraham;3, and &agrab;1D-muscarinic receptors
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Experience from experimental cell transplantation therapy of myocardial infarction: what have we learned?
TL;DR: The experimental data demonstrated that cell transplantation therapy provides a potential approach for the treatment of injured myocardium after myocardial infarction based on the reported positive effects upon histological appearance and left ventricular function.
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Heterogeneity of adult masseter muscle satellite cells with cardiomyocyte differentiation potential
Wei Huang,Jialiang Liang,Yuliang Feng,Zhanfeng Jia,Lin Jiang,Wenfeng Cai,Christian Paul,Jianguo G. Gu,Peter J. Stambrook,Ronald W. Millard,Xiao-Lan Zhu,Ping Zhu,Yigang Wang +12 more
TL;DR: Findings show that MMSCs could serve as a novel cell source for cardiomyocyte replacement without the need for genetic manipulation or invasive heart biopsy procedures.
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Patricia A. Zuk,Min Zhu,Hiroshi Mizuno,Jerry I. Huang,Futrell Jw,Adam J. Katz,Prosper Benhaim,H. P. Lorenz,Marc H. Hedrick +8 more
TL;DR: The data support the hypothesis that a human lipoaspirate contains multipotent cells and may represent an alternative stem cell source to bone marrow-derived MSCs.
Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion
Naohiro Terada,Takashi Hamazaki,Masahiro Oka,Masanori Hoki,Diana M. Mastalerz,Yuka Nakano,Edwin M. Meyer,Laurence Morel,Bryon E. Petersen,Edward W. Scott +9 more
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TL;DR: Using a simple method based on Cre/lox recombination to detect cell fusion events, it is demonstrated that bone-marrow-derived cells (BMDCs) fuse spontaneously with neural progenitors in vitro, raising the possibility that cell fusion may contribute to the development or maintenance of these key cell types.
Mesenchymal stem cells can be differentiated into endothelial cells in vitro.
Joachim Oswald,Sabine Boxberger,Birgitte Jørgensen,Silvia Feldmann,Gerhard Ehninger,Martin Bornhäuser,Carsten Werner +6 more
TL;DR: The differentiation of expanded adult human MSCs into cells with phenotypic and functional features of endothelial cells are shown to provide new options for engineering of artificial tissues based on autologous M SCs and vascularized engineered tissues.
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