Intermittent fasting vs daily calorie restriction for type 2 diabetes prevention: a review of human findings

TL;DR: This review looked at the forms of caloric restriction investigated in randomised controlled trials and found that supervised continuous and intermittent CR was more effective than other forms of weight loss over periods from 12 weeks to 2 years and could improve cardiovascular and diabetes risk factors.

TL;DR: In this paper , the authors evaluated the effect of alternate-day modified fasting on sleep quality, body weight, and daytime sleepiness in women with overweight or obesity and found that the ADMF diet was beneficial for controlling body weight and BMI.

TL;DR: The primary hypothesis was that autophagy promotes chondrocyte survival, so, that inhibition of this process may impair the linear growth of bones and promote the development of agerelated osteoarthritis and the improvements in anthropometric and metabolic parameters during long-term intermittent caloric restriction are observed.

TL;DR: In this article, the authors assess prolonged nightly fasting in association with performance-based lower-extremity function (LEF) in a large population of community-dwelling older adults.

TL;DR: Diet and/or exercise interventions led to a significant decrease in the incidence of diabetes over a 6-year period among those with IGT, and thereby reduce the overall incidence of diabetic complications.

TL;DR: The relations between change in adult weight and the risk for noninsulin-dependent diabetes mellitus among women during 14 years of follow-up were quantified.

TL;DR: In this article, the authors explored the contribution of changes in weight, diet, and physical activity on the risk of developing diabetes among ILS participants, and found that weight loss was the dominant predictor of reduced diabetes incidence (hazard ratio per 5-kg weight loss 0.42 [95% CI 0.35-0.51]; P < 0.0001).

TL;DR: It is concluded that long-term intervention in the form of diet and physical exercise is feasible even on a large scale, and that substantial metabolic improvement can be achieved which may contribute to prevent or postpone manifest diabetes.