Intermittent fasting vs daily calorie restriction for type 2 diabetes prevention: a review of human findings

TL;DR: In this article , the authors proposed that repeated oscillations increase insulin secretion and sensitivity, and improve metabolic health in patients with obesity with or without type 2 diabetes (T2DM).

TL;DR: Alternative day fasting is more effective than daily calorie restriction for increasing LDL particle size and how does meal timing during alternate day fasting affect weight loss and coronary heart disease risk in obese adults?

TL;DR: The main research hotspots and frontiers are ADF for obesity and cardiometabolic risk, andADF for several different population groups including healthy adults and patients with diabetes, nonalcoholic fatty liver disease (NAFLD), and cancer.

TL;DR: Diet and/or exercise interventions led to a significant decrease in the incidence of diabetes over a 6-year period among those with IGT, and thereby reduce the overall incidence of diabetic complications.

TL;DR: The relations between change in adult weight and the risk for noninsulin-dependent diabetes mellitus among women during 14 years of follow-up were quantified.

TL;DR: In this article, the authors explored the contribution of changes in weight, diet, and physical activity on the risk of developing diabetes among ILS participants, and found that weight loss was the dominant predictor of reduced diabetes incidence (hazard ratio per 5-kg weight loss 0.42 [95% CI 0.35-0.51]; P < 0.0001).

TL;DR: It is concluded that long-term intervention in the form of diet and physical exercise is feasible even on a large scale, and that substantial metabolic improvement can be achieved which may contribute to prevent or postpone manifest diabetes.