Journal Article10.1002/MAS.20217
Infrared multiple photon dissociation spectroscopy of ions in Penning traps.
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TL;DR: This review describes experiments in which tunable infrared lasers have been used to irradiate ions in Penning traps, and the ionic systems examined have ranged from small hydrocarbons to multiply charged proteins, and they are discussed in approximate order of increasing complexity.
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Abstract: The ability of Paul and Penning traps to contain ions for time periods ranging from milliseconds to minutes allows the trapped ions to be subjected to laser irradiation for extended lengths of time. In this way, relatively low-powered tunable infrared lasers can be used to induce ion fragmentation when a sufficient number of infrared photons are absorbed, a process known as infrared multiple photon dissociation (IRMPD). If ion fragmentation is monitored as a function of laser wavelength, a photodissociation action spectrum can be obtained. The development of widely tunable infrared laser sources, in particular free electron lasers (FELs) and optical parametric oscillators/amplifiers (OPO/As), now allows spectra of trapped ions to be obtained for the entire "chemically relevant" infrared spectral region. This review describes experiments in which tunable infrared lasers have been used to irradiate ions in Penning traps. Early studies which utilized tunable carbon dioxide lasers with a limited output range are first reviewed. More recent studies with either FEL or OPO/A irradiation sources are then covered. The ionic systems examined have ranged from small hydrocarbons to multiply charged proteins, and they are discussed in approximate order of increasing complexity.
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References
•Book
Density-functional theory of atoms and molecules
Robert G. Parr
- 01 Jan 1989
TL;DR: In this paper, a review of current studies in density functional theory and density matrix functional theory is presented, with special attention to the possible applications within chemistry, including the concept of an atom in a molecule, calculation of electronegativities from the Xα method, pressure, Gibbs-Duhem equation, Maxwell relations and stability conditions.
14.8K
Electrospray ionization for mass spectrometry of large biomolecules
TL;DR: Spectra have been obtained for biopolymers including oligonucleotides and proteins, the latter having molecular weights up to 130,000, with as yet no evidence of an upper limit.
7.5K
•Book
A Chemist's Guide to Density Functional Theory
Wolfram Koch,Max C. Holthausen +1 more
- 01 Sep 2001
TL;DR: A Chemist's Guide to Density Functional Theory should be an invaluable source of insight and knowledge for many chemists using DFT approaches to solve chemical problems.
5.2K
Matrix-assisted ultraviolet laser desorption of non-volatile compounds
TL;DR: In this paper, the use of a matrix for pulsed ultraviolet laser desorption mass spectrometry is shown to extend its applicability into the range of larger, thermally labile biomolecules.
2K
Molecular Beams of Macroions
TL;DR: In this article, the authors demonstrate that definite mass/charge states can be formed by electrospraying a dilute polymer solution into an evaporation chamber, negative macroions can be produced and a molecular beam formed by sampling the gaseous mixture of macroions, solvent and nitrogen molecules with a nozzle-skimmer system of the Kantrowitz-Gray type.
1.7K