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Targeting cell death pathways for cancer therapy: recent developments in necroptosis, pyroptosis, ferroptosis, and cuproptosis research
TL;DR: In this article , a review of the potential agents and nanoparticles that induce or inhibit RCD pathways and their therapeutic effects on cancer based on evidence from in vivo and in vitro studies and reports clinical trials in which RCD inducers have been evaluated as treatments for cancer patients.
Ferroptosis, necroptosis, and pyroptosis in the tumor microenvironment: perspectives for immunotherapy of SCLC.
TL;DR: In this paper , the authors summarize the roles of distinct ICD mechanisms on antitumor immunity and recent advances of ferroptosis-, necroptosis-and pyroptotic-inducing agents, and present perspectives on these cell death mechanisms in immunotherapy of small cell lung cancer.
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Neuronal cell death mechanisms in Alzheimer’s disease: An insight
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Novel necroptosis-related gene signature for predicting the prognosis of pancreatic adenocarcinoma
TL;DR: NRGs and the relationship of the immune function, immune checkpoints, and m6A gene expression with NRGs in PAAD may be considered as potential therapeutic targets that should be further studied.
The deubiquitinase USP11 ameliorates intervertebral disc degeneration by regulating oxidative stress-induced ferroptosis via deubiquitinating and stabilizing Sirt3
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Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells
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