Infectivity of Hepatitis B Virus Surface Antigen‐Positive Plasma With Undetectable <scp>HBV</scp>‐<scp>DNA</scp>: Can <scp>HBsAg</scp> Screening Be Discontinued in Egyptian Blood Donors?

TL;DR: It is demonstrated that class I-restricted HBV-specific CTLs profoundly suppress hepatocellular HBV gene expression in HBV transgenic mice by a noncytolytic process, the strength of which greatly exceeds the cytopathic effect of the C TLs in magnitude and duration.

TL;DR: The understanding of the relationship of viral load to infectivity important in applying the I-WP model, it also is important for understanding the potential for transfusion transmission during early recovery and later chronic stages of viral infection.

TL;DR: Thirty-four chimpanzees were inoculated with sera containing the adw, ayw, adr, or ayr subtype of hepatitis B surface antigen (HBs Ag), and in every instance the sub type in the infected animal was the same as the subtype in the inoculum.

TL;DR: The Eurohep Pathobiology Group has established two reference samples of plasma from HBV carriers and determined as accurately as possible the number of HBV DNA molecules in these samples as discussed by the authors.