Journal Article10.1056/NEJMRA010082
Infective endocarditis in adults.
TL;DR: This review article provides a comprehensive assessment of this serious infectious disease, including diagnostic challenges, cardiovascular and neurologic complications, and approaches to therapy.
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Abstract: The clinical features of this complex infection have changed in the past several decades. It is now an infection of older people, and mitral-valve prolapse is the most common predisposing cardiovascular problem in developed countries. In contrast, rheumatic heart disease is an important predisposing problem in developing countries. This review article provides a comprehensive assessment of this serious infectious disease, including diagnostic challenges, cardiovascular and neurologic complications, and approaches to therapy.
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Citations
Non-susceptibility trends among enterococci and non-pneumococcal streptococci from bacteraemias in the UK and Ireland, 2001–06
Derek F. J. Brown,Russell Hope,David M. Livermore,Geraldine Brick,Karen Broughton,Robert George,Rosy Reynolds +6 more
TL;DR: The prevalence of reduced susceptibility in streptococci and enterococci did not change significantly for most antibiotics, but trends were noted to increased ampicillin, imipenem and vancomycin resistance in Enterococcus faecium.
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Using 18-Fluoro-2-Deoxyglucose Positron Emission Tomography in Detecting Infectious Endocarditis/Endoarteritis: A Preliminary Report
TL;DR: FDG- PET appears to be a promising tool in diagnosing infective endocarditis/endoarteritis, and further prospective studies on a large scale are needed to fully exploit the usefulness of FDG-PET for infective Endocarditis-endo arteritis.
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Time-kill behaviour against eight bacterial species and cytotoxicity of antibacterial monomers.
TL;DR: DMADDM and DMAEDM are promising for use in bonding agents and other restorative/preventive materials to combat a variety of oral pathogens.
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CT and MR Imaging of the Aortic Valve: Radiologic-Pathologic Correlation
TL;DR: Surgery is generally recommended for patients with severe stenosis who are symptomatic or who have significant ventricular dysfunction; transcatheter aortic valve implantation is an emerging therapeutic option for patients who are not eligible for surgical treatment.
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Phocine distemper virus in northern sea otters in the Pacific Ocean, Alaska, USA.
Tracey Goldstein,Jonna A. K. Mazet,Verena A. Gill,Angela M. Doroff,Kathy A. Burek,John A. Hammond,John A. Hammond +6 more
TL;DR: It is found that northern sea otters in Alaska are infected with PDV, which has created a disease threat to several sympatric and decreasing Pacific marine mammals.
References
Proposed Modifications to the Duke Criteria for the Diagnosis of Infective Endocarditis
Jennifer S. Li,Daniel J. Sexton,Nathan Mick,Richard E. Nettles,Vance G. Fowler,Thomas J. Ryan,Thomas M. Bashore,G. R. Corey +7 more
TL;DR: Modifications of the Duke criteria for the diagnosis of infective endocarditis are proposed, including that positive Q-fever serology should be changed to a major criterion and the minor criterion "echocardiogram consistent with IE but not meeting major criterion" should be eliminated.
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New criteria for diagnosis of infective endocarditis : Utilization of specific echocardiographic findings. Duke Endocarditis Service
TL;DR: Application of the proposed new criteria increases the number of definite diagnoses and should be useful for more accurate diagnosis and classification of patients with suspected endocarditis and provide better entry criteria for epidemiologic studies and clinical trials.
2.5K
Guidelines for the management of patients with valvular heart disease: executive summary. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients with Valvular Heart Disease)
Robert O. Bonow,Blase A. Carabello,Antonio C. de Leon,L. Henry Edmunds,Bradley J. Fedderly,Michael D. Freed,William H. Gaasch,Charles R. McKay,Rick A. Nishimura,Patrick T. O'Gara,Robert A. O'Rourke,Shahbudin H. Rahimtoola,James L. Ritchie,Melvin D. Cheitlin,Kim A. Eagle,Timothy J. Gardner,Arthur Garson,Raymond J. Gibbons,Richard O. Russell,Thomas J. Ryan,Sidney C. Smith +20 more
TL;DR: These guidelines follow the format established in previous American College of Cardiology/American Heart Association (ACC/AHA) guidelines for classifying indications for diagnostic and therapeutic procedures, and make recommendations for diagnostic testing, treatment, and physical activity.
1.1K
Practice Guidelines for the Treatment of Candidiasis
John H. Rex,Thomas J. Walsh,Jack D. Sobel,Scott G. Filler,Peter G. Pappas,William E. Dismukes,John E. Edwards +6 more
TL;DR: This document summarizes current knowledge about treatment of multiple forms of candidiasis and is the guideline of the Infectious Diseases Society of America for the treatment ofCandida, covering 4 major topical areas.
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Guidelines for the management of patients with valvular heart disease: Executive summary: A report of the American college of cardiology/American heart association task force on practice guidelines (Committee on management of patients with valvular heart disease)
Robert O. Bonow,Blase A. Carabello,Antonio C. de Leon,L. Henry Edmunds,Bradley J. Fedderly,Michael D. Freed,William H. Gaasch,Charles R. McKay,Rick A. Nishimura,Patrick T. O'Gara,Robert A. O'Rourke,Shahbudin H. Rahimtoola,James L. Ritchie,Melvin D. Cheitlin,Kim A. Eagle,Timothy J. Gardner,Arthur Garson,Raymond J. Gibbons,Richard O. Russell,Thomas J. Ryan,Sidney C. Smith +20 more
TL;DR: A report of the 2008 Focused Update Incorporated Into the ACC/AHA 2006 Guidelines for the Valvular Heart Disease : A Report of the2008 Focused update Incorporated into the ACC and AHA 2006 guidelines for management of patients with valvular heart disease.
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