Increasing prevalence of hypervirulent ST5 methicillin susceptible Staphylococcus aureus subtype poses a serious clinical threat.
TL;DR: The ST5 clonotype isolates have dominated S. aureus infections for more than... as discussed by the authors, which is a clinical pathogen of great significance causing metastatic or complicated infections.
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Abstract: Staphylococcus aureus (S. aureus) is a clinical pathogen of great significance causing metastatic or complicated infections. ST5 clonotype isolates have dominated S. aureus infections for more than...
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Citations
Drivers of methicillin-resistant Staphylococcus aureus (MRSA) lineage replacement in China
Hongbin Chen,Hongbin Chen,Yuyao Yin,Lucy van Dorp,Liam P. Shaw,Liam P. Shaw,Hua Gao,Mislav Acman,Jizhen Yuan,Fengning Chen,Shijun Sun,Xiaojuan Wang,Shuguang Li,Yawei Zhang,Rhys A. Farrer,Rhys A. Farrer,Hui Wang,Francois Balloux +17 more
TL;DR: In this paper, the authors investigated the replacement of Staphylococcus aureus (MRSA) using whole-genome sequencing data from 204 ST239 and ST59 isolates collected in Chinese hospitals between 1994 and 2016.
ESKAPE in China: epidemiology and characteristics of antibiotic resistance.
Qixia Luo,Ping Lu,Yunbo Chen,Ping Shen,Bo Zheng,Jinru Ji,Chaoqun Ying,Zhiying Liu,Yonghong Xiao +8 more
TL;DR: The current epidemiology and characteristics of this important group of bacterial pathogens are examined, delving into relevant mechanisms of resistance to recently introduced antibiotics that impact their clinical utility in China.
32
Transcriptome and Proteome of Methicillin-Resistant Staphylococcus aureus Small-Colony Variants Reveal Changed Metabolism and Increased Immune Evasion
Si-Yuan Liu,Honglin Chen,Juan Chen,Tianyi Wang,Shangyu Tu,Xiaoyan Zhang,Qi Wang,Yuyao Yin,Yawei Zhang,Xiaojuan Wang,Chunjiang Zhao,Hui Wang +11 more
TL;DR: In this article , the authors provided proteomic and transcriptomic profiles of clinical MRSA sequence type 239 (ST239) normal strains and SCVs and attempted to identify the key genes or pathways closely related to SCV formation and survival.
14
In vitro antimicrobial activity and resistance mechanisms of the new generation tetracycline agents, eravacycline, omadacycline, and tigecycline against clinical Staphylococcus aureus isolates
Weiliang Zeng,Xiaotuan Zhang,Yang Liu,Yi Zhang,Mengxin Xu,Sipei Wang,Yao Sun,Tieli Zhou,Lijiang Chen +8 more
TL;DR: In this paper , the authors investigated the in vitro activity and resistance mechanisms of the new generation tetracycline agents, namely eravacyclines, omadacy-cline, and tigecycline against Staphylococcus aureus isolates.
Staphylococcus aureus ST1 promotes persistent urinary tract infection by highly expressing the urease
TL;DR: Wang et al. as mentioned in this paper investigated the molecular epidemiology, phenotypic characteristics, and pathophysiology of Staphylococcus aureus-induced UTIs, and analyzed non-repetitive 4,405 S.Aureus isolates collected from various clinical sources from 2008 to 2020 from a general hospital in Shanghai.
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