Open AccessJournal Article
Increased platelet thromboxane synthesis in diabetes mellitus.
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TL;DR: It is concluded that platelets obtained from some diabetic subjects manifest increased synthesis of TXA2, which may contribute to the enhanced platelet aggregation.
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About: This article is published in Journal of Laboratory and Clinical Medicine. The article was published on 01 Jan 1981. and is currently open access. The article focuses on the topics: Thromboxane & Thromboxane-A synthase.
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Citations
Increased arachidonic acid uptake by platelets from insulin-dependent diabetics and diabetic rats
TL;DR: The present results suggest that the increased arachidonic acid uptake by platelets from insulin-dependent diabetic patients and streptozotocin-diabetic rats depends on their increased platelet arachIDonic acid utilization through the cyclooxygenase pathway.
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High heparin released platelet factor 4 in uncomplicated type 1 diabetes mellitus.
Michele Cortellaro,Elisabetta Cofrancesco,A. Vicari,C. Boschetti,A. Della Volpe,G. Moreo,G. Pozza,Elio Polli +7 more
TL;DR: High levels of heparin released-PF4 seem to be an early marker of in vivo increased platelet activation in uncomplicated diabetes mellitus.
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Is aspirin effective in diabetic patients? Yes.
TL;DR: Four major issues are considered in developing the argument that aspirin is effective in diabetic patients, which have let to firm guidelines for its use in people with elevated cardiovascular risk.
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Residual platelet reactivity in atherosclerosis and its impact on patient outcomes
Lisa Renee Johnston
- 01 Jan 2014
TL;DR: The influence of platelets on the immune system and the prevalence of high and low residual platelet reactivity phenotypes and the association of these phenotypes with thrombotic and bleeding risk in acute coronary syndrome patients and patients with atherosclerotic vascular disease were investigated.
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