Open AccessJournal Article
Increased platelet thromboxane synthesis in diabetes mellitus.
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TL;DR: It is concluded that platelets obtained from some diabetic subjects manifest increased synthesis of TXA2, which may contribute to the enhanced platelet aggregation.
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About: This article is published in Journal of Laboratory and Clinical Medicine. The article was published on 01 Jan 1981. and is currently open access. The article focuses on the topics: Thromboxane & Thromboxane-A synthase.
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Citations
Vasoreactivity to prostaglandins of rat peripheral nerve.
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TL;DR: The effect of the local superfusion of prostaglandins E1, I2 and F2 alpha (PGE1, PGI2 and PGF2 alpha, respectively) on rat sciatic nerve blood flow and microvascular resistance was evaluated and appeared to be about 1.5 orders of magnitude less potent than PGE1.
16
Platelet and clotting activities after cold stress in diabetic patients.
TL;DR: These studies indicate that, in the basal state, patients with diabetes or simple carbohydrate intolerance are more susceptible than controls to platelet activation and that after stress thrombin formation can occur although some variability exists among and within groups of patients.
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Plasma 6-keto-PGF1α, thromboxane B2 and PGE2 in Type 1 (insulin-dependent) diabetic patients during exercise
TL;DR: The hypothesis that Type 1 diabetic patients have a decreased capacity of prostanoid production, as suggested from in vitro studies, is not supported.
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Prostacyclin receptor expression on platelets of humans with type 2 diabetes is inversely correlated with hemoglobin A1c levels
TL;DR: It is suggested that reduced IPR expression in DM2 platelets may contribute to platelet hyperactivity in humans with type 2 diabetes.
15
A random-pattern skin-flap model in streptozotocin diabetic rats
TL;DR: It is demonstrated that a 4-week diabetic duration for rats is sufficient to observe diabetes' deleterious effects on the flaps' viability and these effects were significantly established, however, after 8 weeks of diabetes.
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