Increased aggression and activity level in 3- to 11-year-old girls with congenital adrenal hyperplasia (CAH)
Vickie Pasterski,Peter C. Hindmarsh,Mitchell E. Geffner,Charles G. D. Brook,Caroline Brain,Melissa Hines,Melissa Hines +6 more
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TL;DR: Assessment of aggression and activity level in 3- to 11-year-old children with CAH and in their unaffected siblings using a questionnaire that mothers completed to indicate current aggressive behavior and activitylevel suggests that early androgens have a masculinizing effect on bothaggressive behavior andActivity level in girls.
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About: This article is published in Hormones and Behavior. The article was published on 01 Sep 2007. and is currently open access. The article focuses on the topics: Aggression.
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Citations
Hormone-Dependent Chromatin Modifications Related to Sexually Differentiated Behaviors
Khatuna Gagnidze,Donald W. Pfaff +1 more
- 01 Jan 2013
TL;DR: A 3-hit theory of the large sex difference in autism is proposed: genetic predispositions are followed by androgenic hormone effects on CNS arousal systems and limbic forebrain, in young males; followed in turn by deleterious effects of early stress.
5
Assessment of retinal thickness as a marker of brain masculinization in children with congenital adrenal hyperplasia: a pilot study.
Hasan Önal,Esra Kutlu,Banu Kucukemre Aydin,Atilla Ersen,Neval Topal,Erdal Adal,Hatice Güneş,Hilal Doktur,Canan Tanidir,Dilara Pirhan,Nihat Sayın +10 more
TL;DR: Using retinal thickness measurements as a marker of prenatal excess androgen exposure in future studies is suggested, as retina is part of the brain, and appears to be a morphological evidence of the excess androgens exposure on brain structures in girls with CAH.
4
Diagnosis and management of congenital adrenal hyperplasia in the child and adolescent
Ips Kochar,Radhika Jindal +1 more
TL;DR: Congenital adrenal hyperplasia is the most common cause of primary adrenal insufficiency in childhood and undertreatment leads to acute risk of adrenal crisis and to long-term risk of short adult stature and infertility, whereas overtreatment is associated with short stature, obesity and other effects of hypercortisolism.
4
Approach to Children with Aggressive Behavior for General Pediatricians and Hospitalists: Part 1-Epidemiology and Etiology.
TL;DR: The broad differential diagnosis that should be considered when initially evaluating a patient presenting with aggression or altered mental status is discussed; underlying causes include predisposing factors, comorbid conditions, and acute organic causes involving almost every organ system.
4
Affective disorder and hyperandrogenism.
TL;DR: An association between increased androgenic hormone levels in women, quetiapine and lithium carbonate treatment as well as the presence of an affective disorder and premenstrual dysphoric disorder are considered.
4
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Hormones, brain, and behavior
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Congenital adrenal hyperplasia
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TL;DR: Prenatal diagnosis by direct mutation detection permits prenatal treatment of affected females with severe, classic 21-hydroxylase deficiency to minimize genital virilization, reducing mortality from this condition.
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