Journal Article10.1016/J.CARREV.2018.07.021
Incidence and treatment of severe primary mitral regurgitation in contemporary clinical practice.
Stephanie Wu,Audrey L. Chai,Sandra Arimie,Anilkumar Mehra,Leonardo C. Clavijo,Ray V. Matthews,David M. Shavelle +6 more
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TL;DR: Less than half of patients with moderate-severe and severe primary MR received surgery and many were not referred for surgical consultation, suggesting that MR was not addressed by the treating physician and lost to clinical follow-up.
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About: This article is published in Cardiovascular Revascularization Medicine. The article was published on 24 Jul 2018. The article focuses on the topics: MitraClip & Cardiothoracic surgery.
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Citations
Randomized Comparison of Transcatheter Edge-to-Edge Repair for Degenerative Mitral Regurgitation in Prohibitive Surgical Risk Patients.
D. Scott Lim,Robert Smith,Linda D. Gillam,Firas Zahr,Scott M. Chadderdon,Raj Makkar,Ralph Stephan von Bardeleben,Robert Kipperman,Andrew N. Rassi,Molly Szerlip,Scott M. Goldman,Ignacio Inglessis-Azuaje,Pradeep Yadav,Philipp Lurz,Charles J. Davidson,Mubashir Mumtaz,Hemal Gada,Saibal Kar,Susheel Kodali,Roger J. Laham,William Hiesinger,Neil Fam,Mirjam Keßler,William W. O'Neill,Brian Whisenant,Chad Kliger,Samir R. Kapadia,Volker Rudolph,J. B. Choo,James B. Hermiller,Michael Morse,Niklas Schofer,Sameer Gafoor,Azeem Latib,Konstantinos Koulogiannis,Leo Marcoff,Jörg Hausleiter +36 more
TL;DR: The CLASP IID randomized trial as discussed by the authors evaluated the safety and effectiveness of the PASCAL system compared with the MitraClip system in patients with significant symptomatic DMR.
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An Image-Based Computational Fluid Dynamics Study of Mitral Regurgitation in Presence of Prolapse
Lorenzo Bennati,Christian Vergara,Vincenzo Giambruno,Ivan Fumagalli,Antonio F. Corno,Alfio Quarteroni,Giovanni Puppini,Giovanni Battista Luciani +7 more
TL;DR: In this paper , an imaged-based computational study of the systolic fluid dynamics in presence of mitral valve regurgitation (MVR) was performed with the aim of quantifying different hemodynamic quantities.
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1-Year Outcomes Following Transfemoral Transseptal Transcatheter Mitral Valve Replacement: Intrepid TMVR Early Feasibility Study Results.
Firas Zahr,Howard K. Song,Scott M. Chadderdon,Hemal Gada,Mubashir Mumtaz,Timothy J. Byrne,Merick S. Kirshner,Samin K. Sharma,Susheel Kodali,Isaac George,William Merhi,Leora Yarboro,Paul Sorajja,Vinayak Bapat,Tanvir Bajwa,Eric Weiss,Jeremy J. Thaden,Elizabeth Gearhart,Scott Lim,M. Reardon,David H. Adams,Michael J. Mack,Martin B. Leon +22 more
TL;DR: The early benefits of the Intrepid Transfemoral Transseptal TMVR System were maintained up to 1 year with low mortality, low re-intervention, and near complete elimination of MR, demonstrating a favorable safety profile and durable valve function.
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Mitral valve diseases: Pathophysiology and interventions.
TL;DR: In this article, the authors provide a comprehensive view of mitral valve diseases, their etiology and clinical management, including mitral regurgitation, mitral stenosis, and mitral commissurotomy.
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Numerical simulation of transcatheter mitral valve replacement: The dynamic implication of LVOT obstruction in the valve-in-ring case
01 Nov 2022
TL;DR: In this paper , the structural and hemodynamic response of mitral outflow tract (LVOT) obstruction resulting from transcatheter mitral valve replacement (TMVR) with the Edwards SAPIEN 3 Ultra (S3) device is investigated.
References
2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease
Rick A. Nishimura,Catherine M Otto,Robert O. Bonow,Blase A. Carabello,John P. Erwin,Robert A. Guyton,Patrick T. O'Gara,Carlos E. Ruiz,Nikolaos J. Skubas,Paul Sorajja,Thoralf M. Sundt,James D. Thomas +11 more
TL;DR: The medical profession should play a central role in evaluating evidence related to drugs, devices, and procedures for detection, management, and prevention of disease.
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2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: Executive Summary A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines
Rick A. Nishimura,Catherine M Otto,Robert O. Bonow,Blase A. Carabello,John P. Erwin,Robert A. Guyton,Patrick T. O'Gara,Carlos E. Ruiz,Nikolaos J. Skubas,Paul Sorajja,Thoralf M. Sundt,James D. Thomas +11 more
TL;DR: The next generation of leaders in education and research will be shaped by the experiences of those who have gone before them and will help shape the future of the profession.
Percutaneous Repair or Surgery for Mitral Regurgitation
Ted Feldman,Elyse Foster,Donald D. Glower,Saibal Kar,Michael J. Rinaldi,Peter S. Fail,Richard W. Smalling,Robert J. Siegel,Geoffrey A. Rose,Eric Engeron,Catalin Loghin,Alfredo Trento,Eric R. Skipper,Tommy Fudge,George V. Letsou,Joseph M. Massaro,Laura Mauri +16 more
TL;DR: Although percutaneous repair was less effective at reducing mitral regurgitation than conventional surgery, the procedure was associated with superior safety and similar improvements in clinical outcomes.
1.9K
Percutaneous mitral repair with the MitraClip system: safety and midterm durability in the initial EVEREST (Endovascular Valve Edge-to-Edge REpair Study) cohort.
Ted Feldman,Saibal Kar,Michael Rinaldi,Peter S. Fail,James B. Hermiller,Richard W. Smalling,Patrick L. Whitlow,William A. Gray,Reginald I. Low,Howard C. Herrmann,Scott Lim,Elyse Foster,Donald D. Glower,Everest Investigators +13 more
TL;DR: Percutaneous repair with the MitraClip system can be accomplished with low rates of morbidity and mortality and with acute MR reduction to < 2+ in the majority of patients, and with sustained freedom from death, surgery, or recurrent MR in a substantial proportion.
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What are the characteristics of patients with severe, symptomatic, mitral regurgitation who are denied surgery?
Mariana Mirabel,Bernard Iung,Gabriel Baron,David Messika-Zeitoun,Delphine Detaint,Jean-Louis Vanoverschelde,Butchart Eg,Philippe Ravaud,Alec Vahanian +8 more
TL;DR: Impaired LVEF, older age, and comorbidity were the most striking characteristics of patients who were denied surgery in patients with severe symptomatic mitral regurgitation who are denied surgery.