Immunochemical approach to characterize advanced glycation end products of the Maillard reaction. Evidence for the presence of a common structure.
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TL;DR: The results strongly suggest the presence of a common structure in AGE preparations, regardless of whether AGE products are generated from proteins, amino acids, or monoaminocarboxylic acids.
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About: This article is published in Journal of Biological Chemistry. The article was published on 25 Apr 1991. and is currently open access. The article focuses on the topics: Amadori rearrangement & Maillard reaction.
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Citations
•Journal Article
Expression and function of receptors for advanced glycation end products in bovine corneal endothelial cells
TL;DR: Results show that the accumulation of AGEs in CECs induced apoptosis, in part, by increasing cellular oxidative stress.
71
Physicochemical properties and immunological activities of polysaccharides from both crude and wine-processed Polygonatum sibiricum.
Tingting Sun,Hong Zhang,Ye Li,Yang Liu,Wei Dai,Jie Fang,Cui Cao,Yun Die,Qian Liu,Chunliu Wang,Lintao Zhao,Guiping Gong,Zhongfu Wang,Linjuan Huang +13 more
TL;DR: It is found that PSPC and PSPW enhanced the immune functions of the immunosuppressive model for spleen deficient mice and reversed the decline of the secretions of IL-2, IL-6, TNF-α, and IFN-γ to a normal range.
69
Membrane proteins of human erythrocytes are modified by advanced glycation end products during aging in the circulation.
TL;DR: Results indicate that membrane proteins of circulating erythrocytes undergo CML-modification, and the modified proteins accumulated in an age-dependent manner during the life span of ery Throcytes.
69
Perspective of Advanced Glycation End Products on Human Health.
TL;DR: Investigation of the effects of AGE intake-induced variations of gut microbiota on disease progression will further explain the impact of A GEs on health and open a new chapter in AGE research.
69
Advanced Glycation End Products in the Skin: Molecular Mechanisms, Methods of Measurement, and Inhibitory Pathways
TL;DR: In this paper , the formation and characteristics of advanced glycation end products (AGEs) are identified and summarised, focussing on the molecular mechanisms by which AGEs affect the composition and structure of normal skin substances at different skin layers and induce skin issues.
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