Immune modulation of the hypothalamic-pituitary-adrenal (HPA) axis during viral infection.
TL;DR: This review concentrates on the other side of the bi-directional loop of neuroendocrine-immune interactions, namely, the characterization of HPA axis activity during viral infection and the mechanisms employed by cytokines to stimulate glucocorticoid release.
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Abstract: Compelling data has been amassed indicating that soluble factors, or cytokines, emanating from the immune system can have profound effects on the neuroendocrine system, in particular the hypothalam...
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Immunobiology: The Immune System in Health and Disease
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Cellular and Molecular Immunology
Abul K. Abbas,Andrew H. Lichtman,Shiv Pillai +2 more
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TL;DR: Cellular and molecular immunology , Cellular and molecular Immunology , کتابخانه الکرونیک و دیجیتال - آذرسا
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Physiological Functions of Glucocorticoids in Stress and Their Relation to Pharmacological Actions
TL;DR: It is proposed that stress-induced increases in glucocorticoid levels protect not against the source of stress itself but rather against the body's normal reactions to stress, preventing those reactions from overshooting and themselves threatening homeostasis.
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Primary structure and expression of a functional human glucocorticoid receptor cDNA
Stanley M. Hollenberg,Stanley M. Hollenberg,Cary Weinberger,Estelita S. Ong,G Cerelli,Anthony E. Oro,Roger V. Lebo,E B Thompson,Michael G. Rosenfeld,Ronald M. Evans +9 more
TL;DR: Identification of complementary DNAs encoding the human glucocorticoid receptor predicts two protein forms, of 777 (α) and 742 (β) amino acids, which differ at their carboxy termini, which may define the DNA-binding domain.