Immediate treatment with propranolol decreases posttraumatic stress disorder two months after trauma

TL;DR: It is suggested that the acute post-trauma period constitutes a 'window of opportunity' during which treatment of sleep disturbances may be especially effective for preventing or mitigating progression of aberrant psychophysiological processes.

TL;DR: This chapter reviews neuroscience models and evidence on human trauma response, highlighting the need for a refined definition of resilience and closer study of resilient populations to develop effective means for managing trauma aftermath from a neuroscience perspective.

TL;DR: Memory manipulation is discussed, which suggests that using such an intervention could, in principle, help people who suffer from post-traumatic stress disorder, but the idea of doing so is controversial.

TL;DR: The evidence for the effectiveness of propranolol in the prophylaxis and treatment of PTSD and the ethical implications of research on these treatment approaches are discussed.

TL;DR: The Mini International Neuropsychiatric Interview (MINI) as mentioned in this paper is a short diagnostic structured interview (DSI) developed in France and the United States to explore 17 disorders according to Diagnostic and Statistical Manual (DSM)-III-R diagnostic criteria.

TL;DR: The results supported the validity and reliability of the MINI and the application of short structured interviews in clinical and research settings is discussed.

TL;DR: The impairment of propranolol on memory of the emotional story was not due either to reduced emotional responsiveness or to nonspecific sedative or attentional effects, which support the hypothesis that enhanced memory associated with emotional experiences involves activation of the β-adrenergic system.

TL;DR: These pilot results suggest that acute, posttrauma propranolol may have a preventive effect on subsequent PTSD.