Patent
Imaging Systems Featuring Waveguiding Compensation
Wael Yared,Pouyan Mohajerani,Joshua Kempner +2 more
- 03 Jun 2008
25
TL;DR: In this article, the authors proposed a method for altering an image to compensate for variation in one or more physical and/or supervenient properties (e.g., optical absorption and scattering) in heterogeneous, diffuse tissue, thereby attenuating the effects of tissue waveguiding.
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Abstract: In certain embodiments, the invention relates to systems and methods for altering an image to compensate for variation in one or more physical and/or supervenient properties (e.g., optical absorption and/or scattering) in heterogeneous, diffuse tissue, thereby attenuating the effects of tissue waveguiding. The methods enable the proper identification of emission image regions that evidence waveguiding of electromagnetic radiation, and enables compensation of emission images for such waveguiding. The methods preserve the depth localization accuracy of the FMT approach and improve optical reconstruction in the targeted areas while eliminating spurious components of fluorescence from the acquired data set. Calibration methods for probe concentration mapping are also presented.
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Citations
Patent
Quantitative multi-spectral opto-acoustic tomography (msot) of tissue biomarkers
Daniel Razansky,Vasilis Ntziachristos +1 more
- 25 Jul 2008
TL;DR: In this article, a method of multi-spectral opto-acoustic tomography (MSOT) imaging of a target tissue including a target biomarker comprises the steps of illuminating the target tissue with an illumination device emitting at least one pulsed illumination pattern at several illumination wavelengths.
57
Patent
Imaging device and method for optoacoustic imaging of small animals
Daniel Razansky,Vasilis Ntziachristos +1 more
- 23 Jul 2010
TL;DR: In this article, an imaging device (100) was configured for optoacoustic imaging of an object (1) consisting of an illumination device (10) including optical components arranged for illuminating the object, a detector device (20) arranged for detecting acoustic signals created in the object and a container device (50) including a tank and a holding device arranged for accommodating the detector device, the object(1), and a matching transmission medium (53).
56
Patent
Thermoacoustic imaging with quantitative extraction of absorption map
Daniel Razansky,Vasilis Ntziachristos,Amir Rosenthal +2 more
- 29 Jun 2009
TL;DR: In this paper, a method of thermo-acoustic imaging of an object includes providing thermoacoustic signals representing a mechanical wave response to a delivery of electromagnetic energy into the imaged object, reconstructing an energy deposition image representing a local energy absorption within the object, and decomposing the image into a quantitative absorption image.
26
Patent
System and method for quality-enhanced high-rate optoacoustic imaging of an object
Stefan Morscher,Vasilis Ntziachristos,Nikolaos C. Deliolanis +2 more
- 27 Dec 2013
TL;DR: In this paper, the authors describe systems and methods for optoacoustic imaging of an object comprising, in some embodiments, an image acquisition unit for acquiring a first sequence of tomographic opto-acoustic images.
26
Patent
Handheld device and method for tomographic optoacoustic imaging of an object
Marcin Kacprowicz
- 10 Dec 2013
TL;DR: In this article, a handheld device and an according method for optoacoustic imaging of an object, comprising an irradiation unit for irradiating the object with electromagnetic radiation, for example, light, and a detector unit for detecting acoustic, for instance, ultrasonic, waves generated in the object upon irradiation with EM radiation, wherein the detector unit comprises an array of detector elements.
22
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