Journal Article10.1056/NEJM199412083312307
Idiopathic Dilated Cardiomyopathy
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TL;DR: Idiopathic dilated cardiomyopathy is a primary myocardial disease of unknown cause characterized by left ventricular or biventricular dilatation and impairedMyocardial contractility.
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Abstract: Idiopathic dilated cardiomyopathy (IDC) is a primary myocardial disease of unknown cause characterized by left ventricular or biventricular dilatation and impaired myocardial contractility1. Depend...
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Citations
Differentiating Athlete’s Heart From Cardiomyopathies — The Left Side
Maria J. Brosnan,Dhrubo Rakhit +1 more
TL;DR: This chapter will focus on the left side of the heart, where left ventricular cavity enlargement, increase inLeft ventricular wall thickness and increasedleft ventricular trabeculation associated with athletic remodelling may sometimes be difficult to differentiate from conditions such as dilated cardiomyopathy, hypertrophic cardiomeopathy or isolated left Ventricular non-compaction.
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Familial Dilated Cardiomyopathy
TL;DR: To the Editor: The article by Ichihara and colleagues described an association between a G994→T missense mutation in the plasma platelet-activating factor acetylhydrolase gene and genetic susceptibility to nonfamilial dilated cardiomyopathy (DCM).
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Increased 99mTc-Sestamibi Washout Reflects Impaired Myocardial Contractile and Relaxation Reserve During Dobutamine Stress Due to Mitochondrial Dysfunction in Dilated Cardiomyopathy Patients
Daisuke Hayashi,Satoru Ohshima,Satoshi Isobe,Xian Wu Cheng,Kazumasa Unno,Hidehito Funahashi,Norihiro Shinoda,Takahiro Okumura,Akihiro Hirashiki,Katsuhiko Kato,Toyoaki Murohara +10 more
TL;DR: Increased (99m)Tc-MIBI washout may predict mitochondrial dysfunction and the impairment of myocardial contractile and relaxation reserves during dobutamine stress in DCM patients.
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Segmental pattern of myocardial sympathetic denervation in idiopathic dilated cardiomyopathy: relationship to regional wall motion and myocardial perfusion abnormalities
Fragiskos I. Parthenakis,V.K. Prassopoulos,Sophia Koukouraki,Evangelos A. Zacharis,G. F. Diakakis,N.K. Karkavitsas,Panagiotis Vardas +6 more
TL;DR: Patients with idiopathic dilated cardiomyopathy show not only global but also regional abnormalities of cardiac sympathetic innervation and the severity of these changes is partially correlated with abnormalities of regional wall motion and myocardial perfusion.
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Beta 1-adrenergic receptor-directed autoimmunity as a cause of dilated cardiomyopathy in rats.
TL;DR: Recent evidence obtained from experimental animal-models implying a significant role of the cardiac beta(1)-adrenergic receptor as a pathophysiologically and clinically relevant autoantigen also in human DCM is reviewed.
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